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Nitroso Amlodipine EP Impurity B

SZ CAT No SZ-A005059
CAS No NA
Mol.F. C29H31ClN4O8
Mol.Wt. 599.0
Inv. Status Custom Synthesis


Chemical Name: 3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-((2-(2-(methylcarbamoyl)benzamido)ethoxy)methyl)-1-nitroso-1,4-dihydropyridine-3,5-dicarboxylate

Smiles: O=NN(C(C)=C1C(OC)=O)C(COCCNC(C2=C(C(NC)=O)C=CC=C2)=O)=C(C(OCC)=O)C1C3=C(Cl)C=CC=C3

Inchi: InChI=1/C28H26ClN3O8/c1-4-40-28(36)24-21(15-39-14-13-31-25(33)17-9-5-6-10-18(17)26(31)34)32(30-37)16(2)22(27(35)38-3)23(24)19-11-7-8-12-20(19)29/h5-12,23H,4,13-15H2,1-3H3

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.
 
Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344
 
Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9