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N-Nitroso paroxetine Impurity

SZ CAT No SZ-P012026
CAS No 2361294-43-9
Mol.F. C19H19FN2O4
Mol.Wt. 358.4
Inv. Status In Stock

Chemical Name: (3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-1-nitrosopiperidine

Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)
Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolff
Journal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089
An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form
M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig
Cryst. Growth Des. 2014, 14, 8, 3774–3782
Determination of residual solvents in paroxetine by headspace gas chromatography
abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy
Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155
Spectral Characterization of Degradation Impurities of Paroxetine Hydrochloride Hemihydrate
nirmala munigela, j. moses babu , anjaneyulu yerramilli , naveen kumar kolla , vyas krishnamurthy, vijay vittal mathad
Sci Pharm. 2008; 76; 653–661.