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N-Nitroso Amlodipine Impurity-1

SZ CAT No SZ-A005065
CAS No NA
Mol.F. C20H21ClN2O6
Mol.Wt. 420.8
Inv. Status Under Synthesis


Chemical Name: 5-Ethyl 7-methyl 6-(2-chlorophenyl)-8-methyl-4-nitroso-3,4,6,7-tetrahydro-2H-benzo[b][1,4]oxazine-5,7-dicarboxylate

Smiles: ClC1=CC=CC=C1C2C(C(OCC)=O)=C(N(N=O)CCO3)C3=C(C)C2C(OC)=O

Inchi: InChI=1S/C19H23NO3/c1-19(2)22-13-16-10-15(8-9-18(16)23-19)17(21)12-20-11-14-6-4-3-5-7-14/h3-10,17,20-21H,11-13H2,1-2H3/t17-/m0/s1

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.
 
Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344
 
Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9