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Pharmaceutical Reference Standards

Methotrexate Dihydrate

Picture of Methotrexate Dihydrate
CAT No: SZ-M019001
CAS No: 1212284-68-8
Mol.F. : C20H22N8O5 : 2(H2O)
Mol.Wt. : 454.4 : 2(18.0)
Inv. Status: In Stock
Rel. CAS No : 59-05-2 (free base)
SZ-M019001
CAS No:1212284-68-8
Mol.F.: C20H22N8O5 : 2(H2O)
Mol.Wt.: 454.4 : 2(18.0)
Inv. Status: In Stock
Rel. CAS No : 59-05-2 (free base)

Methotrexate EP Impurity A

Picture of Methotrexate EP Impurity A
CAT No: SZ-M019002
CAS No: 945-24-4
Mol.F. : C7H8N6O
Mol.Wt. : 192.1
Inv. Status: In Stock
Rel. CAS No : 73978-41-3 (HCl salt)
SZ-M019002
CAS No:945-24-4
Mol.F.: C7H8N6O
Mol.Wt.: 192.1
Inv. Status: In Stock
Rel. CAS No : 73978-41-3 (HCl salt)

Methotrexate Hydrate EP Impurity B

Picture of Methotrexate Hydrate EP Impurity B
CAT No: SZ-M019003
CAS No: 1217459-90-9
Mol.F. : C19H20N8O5 : H2O
Mol.Wt. : 440.4 : 18.0
Inv. Status: In Stock
Rel. CAS No : 54-62-6 (free base)
SZ-M019003
CAS No:1217459-90-9
Mol.F.: C19H20N8O5 : H2O
Mol.Wt.: 440.4 : 18.0
Inv. Status: In Stock
Rel. CAS No : 54-62-6 (free base)

Methotrexate EP Impurity C

Picture of Methotrexate EP Impurity C
CAT No: SZ-M019004
CAS No: 2410-93-7
Mol.F. : C20H21N7O6
Mol.Wt. : 455.4
Inv. Status: In Stock
SZ-M019004
CAS No:2410-93-7
Mol.F.: C20H21N7O6
Mol.Wt.: 455.4
Inv. Status: In Stock

Methotrexate EP Impurity D

Picture of Methotrexate EP Impurity D
CAT No: SZ-M019005
CAS No: 5623-18-7
Mol.F. : C15H14N6O3
Mol.Wt. : 326.3
Inv. Status: In Stock
SZ-M019005
CAS No:5623-18-7
Mol.F.: C15H14N6O3
Mol.Wt.: 326.3
Inv. Status: In Stock

Methotrexate EP Impurity E

Picture of Methotrexate EP Impurity E
CAT No: SZ-M019006
CAS No: 19741-14-1
Mol.F. : C15H15N7O2
Mol.Wt. : 325.3
Inv. Status: In Stock
SZ-M019006
CAS No:19741-14-1
Mol.F.: C15H15N7O2
Mol.Wt.: 325.3
Inv. Status: In Stock

Methotrexate EP Impurity F

Picture of Methotrexate EP Impurity F
CAT No: SZ-M019007
CAS No: 51865-79-3
Mol.F. : C20H22N8O5
Mol.Wt. : 454.4
Inv. Status: In Stock
SZ-M019007
CAS No:51865-79-3
Mol.F.: C20H22N8O5
Mol.Wt.: 454.4
Inv. Status: In Stock

Methotrexate EP Impurity G

Picture of Methotrexate EP Impurity G
CAT No: SZ-M019008
CAS No: 2519848-42-9
Mol.F. : C28H29N9O6
Mol.Wt. : 587.6
Inv. Status: In Stock
SZ-M019008
CAS No:2519848-42-9
Mol.F.: C28H29N9O6
Mol.Wt.: 587.6
Inv. Status: In Stock

Methotrexate EP Impurity H

Picture of Methotrexate EP Impurity H
CAT No: SZ-M019009
CAS No: 67022-39-3
Mol.F. : C21H24N8O5
Mol.Wt. : 468.5
Inv. Status: In Stock
SZ-M019009
CAS No:67022-39-3
Mol.F.: C21H24N8O5
Mol.Wt.: 468.5
Inv. Status: In Stock

Methotrexate EP Impurity I

Picture of Methotrexate EP Impurity I
CAT No: SZ-M019010
CAS No: 66147-29-3
Mol.F. : C21H24N8O5
Mol.Wt. : 468.5
Inv. Status: In Stock
SZ-M019010
CAS No:66147-29-3
Mol.F.: C21H24N8O5
Mol.Wt.: 468.5
Inv. Status: In Stock

Methotrexate EP Impurity J

Picture of Methotrexate EP Impurity J
CAT No: SZ-M019011
CAS No: 34378-65-9
Mol.F. : C22H26N8O5
Mol.Wt. : 482.5
Inv. Status: In Stock
SZ-M019011
CAS No:34378-65-9
Mol.F.: C22H26N8O5
Mol.Wt.: 482.5
Inv. Status: In Stock

Methotrexate EP Impurity L

Picture of Methotrexate EP Impurity L
CAT No: SZ-M019013
CAS No: 52980-68-4
Mol.F. : C13H16N2O5
Mol.Wt. : 280.3
Inv. Status: In Stock
SZ-M019013
CAS No:52980-68-4
Mol.F.: C13H16N2O5
Mol.Wt.: 280.3
Inv. Status: In Stock

Methotrexate 7-Hydroxy Metabolite

Picture of Methotrexate 7-Hydroxy Metabolite
CAT No: SZ-M019014
CAS No: 5939-37-7
Mol.F. : C20H22N8O6
Mol.Wt. : 470.4
Inv. Status: Limited Stock
SZ-M019014
CAS No:5939-37-7
Mol.F.: C20H22N8O6
Mol.Wt.: 470.4
Inv. Status: Limited Stock

Methotrexate N-Desmethyl Impurity

Picture of Methotrexate N-Desmethyl Impurity
CAT No: SZ-M019015
CAS No: 1189252-22-9
Mol.F. : C14H12N6O3 : H2O
Mol.Wt. : 312.3 : 18.0
Inv. Status: Limited Stock
Rel. CAS No : 119-24-4 (free base)
SZ-M019015
CAS No:1189252-22-9
Mol.F.: C14H12N6O3 : H2O
Mol.Wt.: 312.3 : 18.0
Inv. Status: Limited Stock
Rel. CAS No : 119-24-4 (free base)

N-(4-hydroxybenzoyl)-L-Glutamic acid

Picture of N-(4-hydroxybenzoyl)-L-Glutamic acid
CAT No: SZ-M019016
CAS No: 119843-02-6
Mol.F. : C12H13NO6
Mol.Wt. : 267.2
Inv. Status: Custom Synthesis
SZ-M019016
CAS No:119843-02-6
Mol.F.: C12H13NO6
Mol.Wt.: 267.2
Inv. Status: Custom Synthesis

Methotrexate EP Impurity A (HCl salt)

Picture of Methotrexate EP Impurity A (HCl salt)
CAT No: SZ-M019018
CAS No: 73978-41-3
Mol.F. : C7H8N6O : HCl
Mol.Wt. : 192.2 : 36.5
Inv. Status: In Stock
Rel. CAS No : 945-24-4 (free base)
SZ-M019018
CAS No:73978-41-3
Mol.F.: C7H8N6O : HCl
Mol.Wt.: 192.2 : 36.5
Inv. Status: In Stock
Rel. CAS No : 945-24-4 (free base)

Methotrexate Dimethylamide

Picture of Methotrexate Dimethylamide
CAT No: SZ-M019019
CAS No: 71074-44-7
Mol.F. : C22H27N9O4
Mol.Wt. : 481.5
Inv. Status: Out of Stock
SZ-M019019
CAS No:71074-44-7
Mol.F.: C22H27N9O4
Mol.Wt.: 481.5
Inv. Status: Out of Stock

2,4-Diaminopteridine

Picture of 2,4-Diaminopteridine
CAT No: SZ-M019020
CAS No: 1127-93-1
Mol.F. : C6H6N6
Mol.Wt. : 162.2
Inv. Status: Custom Synthesis
SZ-M019020
CAS No:1127-93-1
Mol.F.: C6H6N6
Mol.Wt.: 162.2
Inv. Status: Custom Synthesis

6-Methyl-2,4-pteridinediamine 

Picture of 6-Methyl-2,4-pteridinediamine 
CAT No: SZ-M019021
CAS No: 708-74-7
Mol.F. : C7H8N6
Mol.Wt. : 176.2
Inv. Status: Custom Synthesis
SZ-M019021
CAS No:708-74-7
Mol.F.: C7H8N6
Mol.Wt.: 176.2
Inv. Status: Custom Synthesis

N-(4-chlorobenzoyl)-L-glutamic acid

Picture of N-(4-chlorobenzoyl)-L-glutamic acid
CAT No: SZ-M019022
CAS No: 57444-70-9
Mol.F. : C12H12ClNO5
Mol.Wt. : 285.7
Inv. Status: Custom Synthesis
SZ-M019022
CAS No:57444-70-9
Mol.F.: C12H12ClNO5
Mol.Wt.: 285.7
Inv. Status: Custom Synthesis

S-methylaminobenzoyl glutamicester

Picture of S-methylaminobenzoyl glutamicester
CAT No: SZ-M019023
CAS No: 2378-95-2
Mol.F. : C17H24N2O5
Mol.Wt. : 336.4
Inv. Status: Custom Synthesis
SZ-M019023
CAS No:2378-95-2
Mol.F.: C17H24N2O5
Mol.Wt.: 336.4
Inv. Status: Custom Synthesis

Methotrexate Impurity 1

Picture of Methotrexate Impurity 1
CAT No: SZ-M019024
CAS No: 1029980-84-4
Mol.F. : C17H24N2O5
Mol.Wt. : 336.4
Inv. Status: Custom Synthesis
SZ-M019024
CAS No:1029980-84-4
Mol.F.: C17H24N2O5
Mol.Wt.: 336.4
Inv. Status: Custom Synthesis

Methotrexate Impurity 2

Picture of Methotrexate Impurity 2
CAT No: SZ-M019025
CAS No: 51865-66-8
Mol.F. : C17H24N2O5
Mol.Wt. : 336.4
Inv. Status: Custom Synthesis
SZ-M019025
CAS No:51865-66-8
Mol.F.: C17H24N2O5
Mol.Wt.: 336.4
Inv. Status: Custom Synthesis

Methotrexate EP Impurity B

Picture of Methotrexate EP Impurity B
CAT No: SZ-M019026
CAS No: 54-62-6
Mol.F. : C19H20N8O5
Mol.Wt. : 440.4
Inv. Status: In Stock
Rel. CAS No : 1217459-90-9 (hydrate)
SZ-M019026
CAS No:54-62-6
Mol.F.: C19H20N8O5
Mol.Wt.: 440.4
Inv. Status: In Stock
Rel. CAS No : 1217459-90-9 (hydrate)

Methotrexate Impurity 3

Picture of Methotrexate Impurity 3
CAT No: SZ-M019027
CAS No: NA
Mol.F. : C25H31N3O6
Mol.Wt. : 469.5
Inv. Status: Custom Synthesis
SZ-M019027
CAS No:NA
Mol.F.: C25H31N3O6
Mol.Wt.: 469.5
Inv. Status: Custom Synthesis

(+/-)Amethopterin

Picture of (+/-)Amethopterin
CAT No: SZ-M019030
CAS No: 60388-53-6
Mol.F. : C20H22N8O5
Mol.Wt. : 454.4
Inv. Status: Custom Synthesis
SZ-M019030
CAS No:60388-53-6
Mol.F.: C20H22N8O5
Mol.Wt.: 454.4
Inv. Status: Custom Synthesis

Methotrexate Disodium Tetrahydrate

Picture of Methotrexate Disodium Tetrahydrate
CAT No: SZ-M019034
CAS No: NA
Mol.F. : C20H20N8O52 : 2(Na) : 4(H2O)
Mol.Wt. : 452.4 : 2(23.0) : 4(18.0)
Inv. Status: In Stock
Rel. CAS No : 59-05-2 (free base) ; 7413-34-5 (disodium salt)
SZ-M019034
CAS No:NA
Mol.F.: C20H20N8O52 : 2(Na) : 4(H2O)
Mol.Wt.: 452.4 : 2(23.0) : 4(18.0)
Inv. Status: In Stock
Rel. CAS No : 59-05-2 (free base) ; 7413-34-5 (disodium salt)

Methotrexate

Picture of Methotrexate
CAT No: SZ-M019035
CAS No: 59-05-2
Mol.F. : C20H22N8O5
Mol.Wt. : 454.4
Inv. Status: In Stock
Rel. CAS No : 6745-93-3 (hydrate salt)
SZ-M019035
CAS No:59-05-2
Mol.F.: C20H22N8O5
Mol.Wt.: 454.4
Inv. Status: In Stock
Rel. CAS No : 6745-93-3 (hydrate salt)

Methotrexate Impurity 4

Picture of Methotrexate Impurity 4
CAT No: SZ-M019036
CAS No: 52030-86-1
Mol.F. : C13H16N2O5
Mol.Wt. : 280.3
Inv. Status: Custom Synthesis
SZ-M019036
CAS No:52030-86-1
Mol.F.: C13H16N2O5
Mol.Wt.: 280.3
Inv. Status: Custom Synthesis

Methotrexate Impurity 5

Picture of Methotrexate Impurity 5
CAT No: SZ-M019037
CAS No: 4215-07-0
Mol.F. : C7H8N6
Mol.Wt. : 176.2
Inv. Status: Custom Synthesis
SZ-M019037
CAS No:4215-07-0
Mol.F.: C7H8N6
Mol.Wt.: 176.2
Inv. Status: Custom Synthesis

Methotrexate Impurity 6

Picture of Methotrexate Impurity 6
CAT No: SZ-M019038
CAS No: NA
Mol.F. : C8H10N6O2
Mol.Wt. : 222.2
Inv. Status: Custom Synthesis
SZ-M019038
CAS No:NA
Mol.F.: C8H10N6O2
Mol.Wt.: 222.2
Inv. Status: Custom Synthesis

Methotrexate Impurity 7

Picture of Methotrexate Impurity 7
CAT No: SZ-M019040
CAS No: 57963-63-0
Mol.F. : C16H21NO6
Mol.Wt. : 323.3
Inv. Status: Custom Synthesis
SZ-M019040
CAS No:57963-63-0
Mol.F.: C16H21NO6
Mol.Wt.: 323.3
Inv. Status: Custom Synthesis

Methotrexate Impurity 8

Picture of Methotrexate Impurity 8
CAT No: SZ-M019041
CAS No: 909874-43-7
Mol.F. : C18H26N2O5
Mol.Wt. : 350.4
Inv. Status: Custom Synthesis
SZ-M019041
CAS No:909874-43-7
Mol.F.: C18H26N2O5
Mol.Wt.: 350.4
Inv. Status: Custom Synthesis

Methotrexate Impurity 9

Picture of Methotrexate Impurity 9
CAT No: SZ-M019042
CAS No: 10541-83-0
Mol.F. : C8H9NO2
Mol.Wt. : 151.2
Inv. Status: Custom Synthesis
SZ-M019042
CAS No:10541-83-0
Mol.F.: C8H9NO2
Mol.Wt.: 151.2
Inv. Status: Custom Synthesis

Methotrexate Impurity 10

Picture of Methotrexate Impurity 10
CAT No: SZ-M019043
CAS No: NA
Mol.F. : C16H20ClNO5
Mol.Wt. : 341.8
Inv. Status: Custom Synthesis
SZ-M019043
CAS No:NA
Mol.F.: C16H20ClNO5
Mol.Wt.: 341.8
Inv. Status: Custom Synthesis

Methotrexate Impurity 11

Picture of Methotrexate Impurity 11
CAT No: SZ-M019044
CAS No: 34794-87-1
Mol.F. : C15H14N6O3
Mol.Wt. : 326.3
Inv. Status: Custom Synthesis
SZ-M019044
CAS No:34794-87-1
Mol.F.: C15H14N6O3
Mol.Wt.: 326.3
Inv. Status: Custom Synthesis

Methotrexate Impurity 12

Picture of Methotrexate Impurity 12
CAT No: SZ-M019053
CAS No: 881-33-4
Mol.F. : C7H8N6O
Mol.Wt. : 192.2
Inv. Status: Custom Synthesis
SZ-M019053
CAS No:881-33-4
Mol.F.: C7H8N6O
Mol.Wt.: 192.2
Inv. Status: Custom Synthesis

Methotrexate Diethyl Ester

Picture of Methotrexate Diethyl Ester
CAT No: SZ-M019054
CAS No: 43170-88-3
Mol.F. : C24H30N8O5
Mol.Wt. : 510.6
Inv. Status: Custom Synthesis
SZ-M019054
CAS No:43170-88-3
Mol.F.: C24H30N8O5
Mol.Wt.: 510.6
Inv. Status: Custom Synthesis

Stable Isotopes and Metabolites

Methotrexate D3

Picture of Methotrexate D3
CAT No: SZ-M019D01
CAS No: 432545-63-6
Mol.F. : C20H19D3N8O5
Mol.Wt. : 457.5
Inv. Status: Custom Synthesis
SZ-M019D01
CAS No:432545-63-6
Mol.F.: C20H19D3N8O5
Mol.Wt.: 457.5
Inv. Status: Custom Synthesis

N-Nitroso Methotrexate EP Impurity B D6

Picture of N-Nitroso Methotrexate EP Impurity B D6
CAT No: SZ-M019D02
CAS No: NA
Mol.F. : C19H13D6N9O6
Mol.Wt. : 475.5
Inv. Status: Under Synthesis
SZ-M019D02
CAS No:NA
Mol.F.: C19H13D6N9O6
Mol.Wt.: 475.5
Inv. Status: Under Synthesis

Possible Nitroso Standards

N-Nitroso Methotrexate EP Impurity-B

Picture of N-Nitroso Methotrexate EP Impurity-B
CAT No: SZ-M019028
CAS No: NA
Mol.F. : C19H19N9O6
Mol.Wt. : 469.4
Inv. Status: In Stock
SZ-M019028
CAS No:NA
Mol.F.: C19H19N9O6
Mol.Wt.: 469.4
Inv. Status: In Stock

N-Nitroso Methotrexate EP Impurity-L

Picture of N-Nitroso Methotrexate EP Impurity-L
CAT No: SZ-M019029
CAS No: NA
Mol.F. : C13H15N3O6
Mol.Wt. : 309.3
Inv. Status: In Stock
SZ-M019029
CAS No:NA
Mol.F.: C13H15N3O6
Mol.Wt.: 309.3
Inv. Status: In Stock

Methotrexate Nitroso Impurity 1

Picture of Methotrexate Nitroso Impurity 1
CAT No: SZ-M019031
CAS No: NA
Mol.F. : C21H21N9O6 : 2(Na)
Mol.Wt. : 495.5 : 2(23.0)
Inv. Status: Custom Synthesis
SZ-M019031
CAS No:NA
Mol.F.: C21H21N9O6 : 2(Na)
Mol.Wt.: 495.5 : 2(23.0)
Inv. Status: Custom Synthesis

N-Nitroso Methotrexate EP Impurity L

Picture of N-Nitroso Methotrexate EP Impurity L
CAT No: SZ-M019032
CAS No: NA
Mol.F. : C13H15N3O6
Mol.Wt. : 309.3
Inv. Status: Custom Synthesis
SZ-M019032
CAS No:NA
Mol.F.: C13H15N3O6
Mol.Wt.: 309.3
Inv. Status: Custom Synthesis

N,N-Dinitroso Methotrexate EP Impurity L

Picture of N,N-Dinitroso Methotrexate EP Impurity L
CAT No: SZ-M019033
CAS No: NA
Mol.F. : C13H14N4O7
Mol.Wt. : 338.3
Inv. Status: Custom Synthesis
SZ-M019033
CAS No:NA
Mol.F.: C13H14N4O7
Mol.Wt.: 338.3
Inv. Status: Custom Synthesis

Methotrexate Nitroso Impurity 2

Picture of Methotrexate Nitroso Impurity 2
CAT No: SZ-M019045
CAS No: NA
Mol.F. : C20H19N9O7
Mol.Wt. : 497.4
Inv. Status: Custom Synthesis
SZ-M019045
CAS No:NA
Mol.F.: C20H19N9O7
Mol.Wt.: 497.4
Inv. Status: Custom Synthesis

N-Nitroso Methotrexate EP Impurity F

Picture of N-Nitroso Methotrexate EP Impurity F
CAT No: SZ-M019046
CAS No: NA
Mol.F. : C20H21N9O6
Mol.Wt. : 483.4
Inv. Status: Custom Synthesis
SZ-M019046
CAS No:NA
Mol.F.: C20H21N9O6
Mol.Wt.: 483.4
Inv. Status: Custom Synthesis

Methotrexate Nitroso Impurity 3

Picture of Methotrexate Nitroso Impurity 3
CAT No: SZ-M019047
CAS No: NA
Mol.F. : C17H23N3O6
Mol.Wt. : 365.4
Inv. Status: Custom Synthesis
SZ-M019047
CAS No:NA
Mol.F.: C17H23N3O6
Mol.Wt.: 365.4
Inv. Status: Custom Synthesis

Methotrexate Nitroso Impurity 4

Picture of Methotrexate Nitroso Impurity 4
CAT No: SZ-M019048
CAS No: NA
Mol.F. : C17H23N3O6
Mol.Wt. : 365.4
Inv. Status: Custom Synthesis
SZ-M019048
CAS No:NA
Mol.F.: C17H23N3O6
Mol.Wt.: 365.4
Inv. Status: Custom Synthesis

Methotrexate Nitroso Impurity 5

Picture of Methotrexate Nitroso Impurity 5
CAT No: SZ-M019049
CAS No: NA
Mol.F. : C17H22N4O7
Mol.Wt. : 394.4
Inv. Status: Custom Synthesis
SZ-M019049
CAS No:NA
Mol.F.: C17H22N4O7
Mol.Wt.: 394.4
Inv. Status: Custom Synthesis

Methotrexate diethyl ester Nitroso Impurity

Picture of Methotrexate diethyl ester Nitroso Impurity
CAT No: SZ-M019050
CAS No: NA
Mol.F. : C24H29N9O6
Mol.Wt. : 539.6
Inv. Status: Custom Synthesis
SZ-M019050
CAS No:NA
Mol.F.: C24H29N9O6
Mol.Wt.: 539.6
Inv. Status: Custom Synthesis

N-Nitroso Methotrexate

Picture of N-Nitroso Methotrexate
CAT No: SZ-M019051
CAS No: NA
Mol.F. : C20H21N9O6
Mol.Wt. : 483.4
Inv. Status: Custom Synthesis
SZ-M019051
CAS No:NA
Mol.F.: C20H21N9O6
Mol.Wt.: 483.4
Inv. Status: Custom Synthesis

N-Nitroso Methotrexate EP Impurity B

Picture of N-Nitroso Methotrexate EP Impurity B
CAT No: SZ-M019052
CAS No: NA
Mol.F. : C19H19N9O6
Mol.Wt. : 469.4
Inv. Status: Custom Synthesis
SZ-M019052
CAS No:NA
Mol.F.: C19H19N9O6
Mol.Wt.: 469.4
Inv. Status: Custom Synthesis