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Melphalan EP Impurity F

SZ CAT No SZ-M003041
CAS No NA
Mol.F. C13H17Cl3N2O2
Mol.Wt. 339.6
Inv. Status Custom Synthesis


Chemical Name: 4-[bis(2-chloroethyl)amino]-3-chloro-L-phenylalanine (as per EP)

Synonym: 3-chloromelphalan

Encapsulation of Chemotherapeutic Drug Melphalan in Cucurbit[7]uril: Effects on Its Alkylating Activity, Hydrolysis, and Cytotoxicity
Gustavo Villarroel-Lecourt, Javiera Carrasco-Carvajal, Felipe Andrade-Villalobos, Fresia Solís-Egaña, Ignacio Merino-San Martín, José Robinson-Duggon, and Denis Fuentealba
ACS Omega 2018, 3, 7, 8337–8343
 
Solution stability of Captisol-stabilized melphalan (Evomela) versus Propylene glycol-based melphalan hydrochloride injection
Ramsharan Singh, Jin Chen, Teresa Miller, Michael Bergren & Rangan Mallik
Pharmaceutical Development and Technology 23(10):1-6