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Irinotecan EP Impurity A Hydrochloride

SZ CAT No SZ-I010028
CAS No 207683-84-9
Mol.F. C31H34N4O6 : HCl
Mol.Wt. 558.6 : 36.5
Inv. Status Custom Synthesis
Rel. CAS No 103816-16-6 (free base) ; 883718-83-0 (Sulfate salt)


Chemical Name: (4S)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate Hydrochloride (as per EP); (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quin oline-3,14(4H,12H)-dione-9-yl (1,4′-bipiperidine)-1′-carboxylate Hydrochloride (as per USP)

Development and validation of Spectrophotometric method and TLC Densitometric Determination of Irinotecan HCl in pharmaceutical dosage forms
SmitaSharma, Mukesh C.Sharma
Arabian Journal of Chemistry Volume 9, Supplement 2, November 2016, Pages S1368-S1372
 
Development of stability indicating HPLC method for the assay of irinotecan in the presence of degradents
A.K.Srivastava*, K.Pallavi, S.Shamshul, S.C.Khurana
ACAIJ, 10(10) 2011 [665-669]
 
Validated Reverse Phase HPLC Method for the Determination of Irinotecan in Pharmaceutical Dosage Forms
Murali balaram v, venkateswara rao j * ,ramakrishna s # sankar ganesh g # and balamurali krishna t
E-Journal of Chemistry Vol. 4, No.1, pp 128-136