Chemical Name: 9-Chloro-6α-fluoro-17β-[[(fluoromethyl)sulfanyl]carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-yl furan-2-carboxylate (as per EP)
Smiles: O=C1C=C[C@@]2(C)C([C@@]([H])(F)C[C@]3([H])[C@]2(Cl)[C@](O)([H])C[C@@]4(C)[C@@]3([H])C[C@@]([H])(C)[C@@]4(C(SCF)=O)OC(C5=CC=CO5)=O)=C1
Inchi: InChI=1S/C29H34F2O7/c1-15(2)37-25(35)29(38-24(34)22-7-6-10-36-22)16(3)11-18-19-13-21(30)20-12-17(32)8-9-26(20,4)28(19,31)23(33)14-27(18,29)5/h6-10,12,15-16,18-19,21,23,33H,11,13-14H2,1-5H3/t16-,18+,19+,21+,23+,26+,27+,28+,29+/m1/s1
Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLC–NMR spectroscopy and HPLC–MS
Nisha Mistry a , Ismail M. Ismail b , Marco S. Smith c , Jeremy K. Nicholson d , John C. Lindon
Journal of Pharmaceutical and Biomedical Analysis 16 (1997) 697–705