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Felodipine D5

SZ CAT No  SZ-F011D02
CAS No 1242281-38-4
Mol.F. C18H14D5Cl2NO4
Mol.Wt. 389.3
Inv. Status Custom Synthesis

Chemical Name: 3-(Ethyl-d5) 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Smiles: O=C(C(C(C(C=CC=C1Cl)=C1Cl)C(C(OC)=O)=C(C)N2)=C2C)OC([2H])([2H])C([2H])([2H])[2H]

Inchi: InChI=1/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3/i4D3

Simultaneous determination of enalapril, felodipine and their degradation products in the dosage formulation by reversed-phase high-performance liquid chromatography using a Spherisorb C8 column
Xue-ZhiQinJoeDeMarcoDominic P.Ip
Journal of Chromatography A Volume 707, Issue 2, 21 July 1995, Pages 245-254
Characterizing the Impact of Hydroxypropylmethyl Cellulose on the Growth and Nucleation Kinetics of Felodipine from Supersaturated Solutions
David E. Alonzo,†,‡ Shweta Raina,† Deliang Zhou,§ Yi Gao,‡ Geoff G. Z. Zhang,*,‡ and Lynne S. Taylor
Cryst. Growth Des. 2012, 12, 3, 1538–1547
Stability Indicating Method for the Determination of Related Substances in Felodipine Solid Dosage Form and in the Drug Substance by RP-HPLC
Manoj Kumar Vadlamudi1,2 and Sangeetha Dhanaraj
Journal of Bioequivalence & Bioavailability Volume 8(4): 153-166 (2016)
Development and validation of UV spectrophotometric method for estimation of process related impurity in felodipine bulk and formulation
Vaibhav M. Thorat*1 , Pawar S. S.2 , Pande V. V.3 , Arote S. R.4 and Musmade Deepak S
Der Pharmacia Lettre, 2015, 7 (4):284-290
Quantitative analysis of the inhibitory effect of HPMC on felodipine crystallization kinetics using population balance modeling
Kaoutar Abbou Oucherif,*a Shweta Raina,b Lynne S. Taylorab and James D. Litster
CrystEngComm, 2013,15, 2197-2205