N-Nitroso Paracetamol

N-Nitroso Paracetamol is chemically N-(4-Hydroxyphenyl)-N-nitrosoacetamide. N-Nitroso Paracetamol is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Paracetamol can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paracetamol.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Thermodynamic properties of paracetamol impurities 4-nitrophenol and 4′-chloroacetanilide and the impact of such impurities on the crystallisation of paracetamol from solution
René R.E.Steendam, LeilaKeshavarz, Briande Souza, Patrick J.Frawley
The Journal of Chemical Thermodynamics Volume 133, June 2019, Pages 85-92
 
Impact of Paracetamol Impurities on Face Properties: Investigating the Surface of Single Crystals Using TOF-SIMS
Sara Ottoboni, Michael Chrubasik, Layla Mir Bruce, Thai Thu Hien Nguyen, Murray Robertson, Blair Johnston,Iain D. H. Oswald, Alastair Florence, and Chris Price
Cryst. Growth Des. 2018, 18, 5, 2750–2758
 
Separation and determination of impurities in paracetamol, codeine and pitophenone in the presence of fenpiverinium in combined suppository dosage form
Jiří Vojta, Pavel Hanzlík, Aleš Jedlička, Pavel Coufal
J Pharm Biomed Anal. 2015 Jan;102:85-92.
 
Effects of a structurally related substance on the crystallization of paracetamol
Ali Saleemi, I. I. Onyemelukwe & Zoltan Nagy
Frontiers of Chemical Science and Engineering volume 7, pages79–87(2013)

• We need to receive valid purchase order with Bill to & Ship to address.
• The quotation ID needs to be mentioned in the purchase order.
• You will receive order confirmation prior to dispatch which need to be verified for any error in product, pack size, prices.

Delivery time:

• In Stock product will dispatch in 24 h after receipt of purchase order. It usually take 2-3 days to receive products in India and 5-6 working days for export customer depending on destination.
• The custom synthesis products would be dispatched as per quoted timeline.

Shipping:

• There will be 100 USD towards logistic charges per shipment if we used our FedEx. There will not be any charge if we use your FedEx/DHL Account. Depending on part shipment logistic charges will be added.
• For countries dispatch by courier is not allowed where product would be dispatched in cargo mode as per agreed Inco term.

Additional Charges:

• Controlled substance charges need to follow as per quotation. The specific inputs are required for controlled substance because regulatory status will differ based on destination.
• Cold Shipment Charges needs to be considered as per quotation.
• For ice pack there are no additional charges.

Technical Queries:

• All technical queries need to raise within 15 days of product receipt. Thereafter it will be our resolved at our discretion.

Reach to Us:

• All communication will be addressed to standards@synzeal.com
• SynZeal emphasize on formal communication which is required for smooth processing of the purchase order. It helps multiple people to remain informed about all details.
• For specific purpose, there are below e-mail address to be used.
  • For New products # standards@synzeal.com
  • Order confirmation # order@synzeal.com
  • Open Order Status # projects@synzeal.com
  • Data related Query # support@synzeal.com
  • Invoice Related Query # sales@synzeal.com
  • Logistic Documents # exports@synzeal.com (For export customer only)
• It is recommended to include standards@synzeal.com always in CC while communicating to other e-mail address.
• SynZeal is committed for promptly responding all communication however if sometime urgent comes us you can use our WhatsApp customer care channel (+91 70690 37751) to reach to customer support team. You can also request call back on WhatsApp and our customer support team will reach to you in defined timeframe.