Nome Químico: (2R)-2-Hydroxy-2-((6aR,7S,8aS,8bR,11aR)-7-hydroxy-6a,8a,10,10-tetramethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bHnaphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)acetic acid;
Sinônimo: Desonide unknown Impurity (RRT 0.68)
Sorrisos: O=C1C=C[C@@]2(C)C(CCC3C2[C@@H](O)C[C@@]4(C)C3C[C@@H]5[C@]4(OC(C)(C)O5)[C@@H](O)C(O)=O)=C1
Inchi: InChI=1S/C24H31BrO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15?,16?,17-,19-,21-,22-,23-,24+/m0/s1
Development of a novel HPLC method for the determination of the impurities in desonide cream and characterization of its impurities by 2D LC-IT-TOF MS
Jian Wanga,b, Shuxian Zhenga, Yu Xua, Haiyan Huc, Minji Shenc, Lan Tang
Journal of Pharmaceutical and Biomedical Analysis 161 (2018) 399–406
Studies on the Stability of Corticosteroids: Degradation of Clobetasol Propionate, Desonide and Hydrocortisone in Topical Formulations by HPLC and UPLC-MS/MS
Kishore Kumar Hotha, Subathra Ramamoorthy1, Hiren Patel
American Journal of Analytical Chemistry, 2020, 11, 147-171