Nome Químico: 2-((5-Bromoquinoxalin-6-yl)(4,5-dihydro-1H-imidazol-2-yl)amino)maleic acid
Sorrisos: O=C(O)/C(N(C1=NCCN1)C2=C(Br)C3=NC=CN=C3C=C2)=C\C(O)=O
Inchi: InChI=1/C15H14BrN5O5/c16-9-8(2-1-7-10(9)18-4-3-17-7)21(15-19-5-6-20-15)11(13(23)24)12(22)14(25)26/h1-4,11-12,22H,5-6H2,(H,19,20)(H,23,24)(H,25,26)
Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma
B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.Prausnitz
Journal of Controlled Release Volume 228, 28 April 2016, Pages 48-57
Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma
Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun
ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999
A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems
Jianguo Sun, Xiuwen Zhang & Taomin Huang
Chemistry Central Journal volume 11, Article number: 62 (2017)
Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Brimonidine Tartrate in Pure Form, Formulations and Preformulation Studies
Prakash Bhagav 1, Pandurang Deshpande 1, Saurabh Pandey 1 , Sajeev Chandran
Der Pharmacia Lettre, 2010, 2(3): 106-122