Chemical Name: (2S,3R)-3-(4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)pentan-2-yl formate
Smiles: O=C1N([C@H](CC)[C@H](C)OC([H])=O)N=CN1C(C=C2)=CC=C2N(CC3)CCN3C4=CC=C(OC[C@@H]5C[C@](C6=C(F)C=C(F)C=C6)(CN7C=NC=N7)OC5)C=C4
Inchi: InChI=1S/C38H42F2N8O5/c1-3-36(27(2)52-26-49)48-37(50)47(25-43-48)32-7-5-30(6-8-32)44-14-16-45(17-15-44)31-9-11-33(12-10-31)51-20-28-19-38(53-21-28,22-46-24-41-23-42-46)34-13-4-29(39)18-35(34)40/h4-13,18,23-28,36H,3,14-17,19-22H2,1-2H3/t27-,28+,36+,38-/m0/s1
Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
Stability-indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-TOF/MS, LC-MS/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..