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Candesartan Nitroso Impurity

SZ CAT No SZ-C011035
Mol.F. C33H33N7O7
Mol.Wt. 639.7
Inv. Status Under Synthesis

Chemical Name: (R)-1-(((cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-((2'-(1-nitroso-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate

Smiles: O=C(O[C@@]([H])(C)OC(OC1CCCCC1)=O)C2=CC=CC(N=C3OCC)=C2N3CC(C=C4)=CC=C4C5=CC=CC=C5C6=NN=NN6N=O

Inchi: InChI=1/C13H17ClN2O2/c1-9(16(15-18)13(2,3)4)12(17)10-6-5-7-11(14)8-10/h5-9H,1-4H3

Investigation and structural elucidation of a process related impurity in candesartan cilexetil by LC/ESI-ITMS and NMR
Bhanu Ramana,∗, Brajesh A. Sharmaa,b, Ganesh Mahale b, Dharmendra Singhb, Ashok Kumar
Journal of Pharmaceutical and Biomedical Analysis 56 (2011) 256–263
Synergistic suppression of tumor angiogenesis by codelivering of VEGF targeted siRNA and candesartan mediated by functionalized carbon nanovectors
Xuefang Ding, Yujie Su, Cheng Wang, Fangrong Zhang, Kerong Chen, Yu Wang, Min Li, and Wei Wang
ACS Appl. Mater. Interfaces 2017, 9, 28, 23353–23369
Identification, Isolation, and Characterization of Five Potential Degradation Impurities in Candesartan Cilexetil Tablets
Arivozhi Mohan1,&, S. Shanmugavel1 , Ajay Goyal1 , B. R. Venkataraman2 , D. Saravanan
Chromatographia volume 69, pages1211–1220(2009)