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Buspirone EP Impurity E HCl

SZ CAT No SZ-B023019
CAS No 257877-46-6
Mol.F. C21H33N5O3 : HCl
Mol.Wt. 403.5 : 36.5
Inv. Status Custom Synthesis


Chemical Name: Buspirone Open Ring Impurity (USP) ; [1-[2-Oxo-2-[[4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl]amino]ethyl] cyclopentyl]acetic acid Hydrochloride ;

Development and validation of a high-performance liquid chromatographic method for the determination of buspirone in pharmaceutical preparations
M. Zaxariou, I. Panderi
Journal of Pharmaceutical and Biomedical Analysis 35 (2004) 41–50
 
Liquid Chromatographic Method for the Analysis of Buspirone HCl and Its Potential Impurities
Murat Kartal, Alaa Khedr, Adel Sakr
Journal of Chromatographic Science, Volume 38, Issue 4, April 2000, Pages 151–156
 
Hybrid triple quadrupole-linear ion trap mass spectrometry in fragmentation mechanism studies: application to structure elucidation of buspirone and one of its metabolites
Mei-Yi Zhang,1∗ Nadia Pace,2 Edward H. Kerns,1 Teresa Kleintop,1 Natasha Kagan1 and Takeo Sakuma2
Journal of mass spectrometry j. Mass Spectrom. 2005; 40: 1017–1029