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Bortezomib Impurity 48

SZ CAT No SZ-B004085
CAS No N/A
Mol.F. C57H69B3N12O9
Mol.Wt. 1098.7
Inv. Status Custom Synthesis


Chemical Name: N,N',N''-((2R,2'R,2''R)-(((1S,1'S,1''S)-(1,3,5,2,4,6-trioxatriborinane-2,4,6-triyl)tris(3-methylbutane-1,1-diyl))tris(azanediyl))tris(1-oxo-3-phenylpropane-1,2-diyl))tris(pyrazine-2-carboxamide)

Analysis of Two Commercially Available Bortezomib Products: Differences in Assay of Active Agent and Impurity Profile
Stephen R. Byrn, Patrick A. Tishmack, Mark J. Milton & Helgi van de Velde
AAPS PharmSciTech volume 12, pages461–467(2011)
 
Isolation, Solubility, and Characterization of D-Mannitol Esters of 4-Methoxybenzeneboronic Acid
Antonio Lopalco 1 , William A. Marinaro 1 , Victor W. Day 2 , Valentino J. Stella
J Pharm Sci. 2017 Feb;106(2):601-610
 
Oxidative Deboronation of the Peptide Boronic Acid Proteasome Inhibitor Bortezomib: Contributions from Reactive Oxygen Species in This Novel Cytochrome P450 Reaction
Jason Labutti,† Ian Parsons,‡ Ron Huang, Gerald Miwa, Liang-Shang Gan, and J. Scott Daniels
Chem. Res. Toxicol. 2006, 19, 539-546