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Amlodipine IP Impurity B

SZ CAT No SZ-A005032
CAS No 400024-08-0
Mol.F. C23H20ClNO6
Mol.Wt. 441.9
Inv. Status Custom Synthesis


Chemical Name: Amlodipine Related Compound (E-Isomer) (Ethyl 2-(2-Chloro-benzylidene)-4-[2-(1,3-dioxo-1,3-Dihydro-Isoindol-2-yl)-Ethoxy

Smiles: CCOC(/C(C(COCCN1C(C2=CC=CC=C2C1=O)=O)=O)=C/C3=CC=CC=C3Cl)=O

Inchi: InChI=1S/C26H35ClN2O10/c1-4-38-26(35)20-16(12-37-10-9-28-24-23(33)22(32)21(31)17(11-30)39-24)29-13(2)18(25(34)36-3)19(20)14-7-5-6-8-15(14)27/h5-8,17,19,21-24,28-33H,4,9-12H2,1-3H3/t17-,19?,21?,22-,23-,24?/m1/s1

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.
 
Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344
 
Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9