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Amlodipine Nitroso Impurity 1

SZ CAT No SZ-A005076
CAS No NA
Mol.F. C20H26ClN3O6
Mol.Wt. 439.9
Inv. Status Discontinued


Chemical Name: 3-Ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1-nitroso-1,2,3,4-tetrahydropyridine-3,5-dicarboxylate

Smiles: NCCOCC(N(N=O)C(C)=C1C(OC)=O)C(C(OCC)=O)C1C2=C(Cl)C=CC=C2

Inchi: InChI=1S/C20H25N7O5S/c1-3-5-15-17-18(24-23-15)20(28)22-19(21-17)14-12-13(6-7-16(14)32-4-2)33(30,31)27-10-8-26(25-29)9-11-27/h6-7,12H,3-5,8-11H2,1-2H3,(H,23,24)(H,21,22,28)

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.
 
Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344
 
Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9