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Amlodipine Impurity 8

SZ CAT No SZ-A005026
CAS No 110962-94-2
Mol.F. C19H18Cl2N2O4
Mol.Wt. 409.3
Inv. Status Custom Synthesis


Chemical Name: 3-(2-Cyanoethyl) 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Smiles: O=C(C(C(C(C=CC=C1Cl)=C1Cl)C(C(OC)=O)=C2C)=C(N2)C)OCCC#N

Inchi: InChI=1/C19H23ClN2O5/c1-11-15(18(23)25-2)16(12-4-6-13(20)7-5-12)17(19(24)26-3)14(22-11)10-27-9-8-21/h4-7,16,22H,8-10,21H2,1-3H3

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.
 
Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344
 
Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9