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3-O-Desethyl-5-O-desmethyl Amlodipine

SZ CAT No SZ-A005040
CAS No 1821498-25-2
Mol.F. C17H19ClN2O5
Mol.Wt. 366.8
Inv. Status Under Synthesis


Chemical Name: 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic Acid; Amlodipine Diacid

Synonym: Amlodipine Besylate ; 3-O-Desethyl-5-O-desmethyl Amlodipine

Smiles: OC(C1=C(C)NC(COCCN)=C(C(O)=O)C1C2=C(Cl)C=CC=C2)=O

Inchi: InChI=1/C20H24ClNO6/c1-4-28-20(25)18-15(11-27-10-9-23)22-12(2)16(19(24)26-3)17(18)13-5-7-14(21)8-6-13/h5-8,17,22-23H,4,9-11H2,1-3H3

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.
 
Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344
 
Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9