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Amlodipine

SZ CAT No SZ-A005066
CAS No 88150-42-9
Mol.F. C20H25ClN2O5
Mol.Wt. 408.9
Inv. Status Custom Synthesis
Rel. CAS No 88150-47-4 (Maleate salt) ; 246852-07-3 (HCl salt) ; 246852-09-5 (HBr salt)


Chemical Name: 3-Ethyl 5-methyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate (as per EP)

Smiles: O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)C1C2=CC=CC=C2Cl)OCC

Inchi: InChI=1S/C9H15N5O3.H/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);/t3-,4+,6-;/m0./s1/i;1+1

Identification and characterization of potential impurities of amlodipine maleate
P. Sudhakar a, M. Nirmala a, J. Moses Babu a,∗, K. Vyas a, Ganta Madhusudan Reddy b, B. Vijaya Bhaskar b, P. Pratap Reddy b, K. Mukkanti c
J. Braz. Chem. Soc., Vol. 19, No. 1, 35-41, 2008.
 
Determination of the Absolute Configuration of the Active Amlodipine Enantiomer as (-)-S: A Correction
Siegfried Goldmann,* Jiirgen Stoltefuss, and Liborius Born
J. Med. Chem. 1992,35,3341-3344
 
Development of a Stability-Indicating HPLC Method for Simultaneous Determination of Amlodipine Besylate and Atorvastatin Calcium in Bulk and Pharmaceutical Dosage Form
Hafez HM*, Elshanawany AA, Abdelaziz LM and Mohram MS
Hafez et al., Pharm Anal Acta 2014, 5:9