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Adefovir Dipivoxil Sulfate Salt

SZ CAT No SZ-A075003
CAS No 220350-52-7
Mol.F. C20H32N5O8P : 1/2(H2SO4)
Mol.Wt. 501.5 : 1/2(98.1)
Inv. Status Custom Synthesis
Rel. CAS No 220350-60-7 (HBr salt) ; 142340-99-6 (free base) ; 220350-68-5 (HCl salt)


Chemical Name: ((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate) Sulfate salt

Synonym: Hepsera ; Preveon ; bis(POM)-PMEA

Smiles: O=[P](OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)COCCN1C(N=CN=C2N)=C2N=C1.O=[S](O)(O)=O

Inchi: InChI=1S/C20H21N5O6.Na.H2O/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);;1H2/t13-;;/m0../s1

A simple and specific stability- indicating RP-​HPLC method for routine assay of adefovir dipivoxil in bulk and tablet dosage form
By Darsazan, Bahar; Shafaati, Alireza; Mortazavi, Seyed Alireza; Zarghi, Afshin
From Iranian Journal of Pharmaceutical Research (2017), 16(1), 132-139

Development and validation of RP-​HPLC method for the determination of adefovir dipivoxil in bulk and in pharmaceutical formulation
By Ahmed, Zaheer; Gopinath, B.; Shetty, A. Sathish Kumar; Sridhar, B. K.
From E-Journal of Chemistry (2009), 6(2), 469-474