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Abemaciclib Nitroso Impurity 1

SZ CAT No SZ-A077002
CAS No NA
Mol.F. C27H31F2N9O
Mol.Wt. 535.6
Inv. Status Custom Synthesis


Chemical Name: N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)nitrous amide

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry
Alejandra Martínez-Chávez,corresponding author1,2 Hilde Rosing,1 Michel Hillebrand,1 Matthijs Tibben,1 Alfred H. Schinkel,2 and Jos H. Beijnen
Anal Bioanal Chem. 2019; 411(20): 5331–5345.