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Abemaciclib D10

SZ CAT No SZ-A077D02
CAS No NA
Mol.F. C27H22D10F2N8
Mol.Wt. 516.7
Inv. Status Custom Synthesis


Chemical Name: N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-(methyl-d3)-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry
Alejandra Martínez-Chávez,corresponding author1,2 Hilde Rosing,1 Michel Hillebrand,1 Matthijs Tibben,1 Alfred H. Schinkel,2 and Jos H. Beijnen
Anal Bioanal Chem. 2019; 411(20): 5331–5345.