Chemical Name: 9-Fluoro-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,11,20-trione;9α-Fluoro-16β-methyl-17α,21-dihydroxypregna-1,4-diene-3,11,20-trione
Synonym: 11-Dehydrobetamethasone; 11-Ketobetamethasone;
Smiles: F[C@@]1([C@]2(C=C3)C)[C@](CCC2=CC3=O)([H])[C@@](C[C@H](C)[C@]4(O)C(CO)=O)([H])[C@]4(C)CC1=O
Inchi: InChI=1S/C22H14N4O6/c27-25(28)17-5-1-15(2-6-17)21-11-9-19(31-21)13-23-24-14-20-10-12-22(32-20)16-3-7-18(8-4-16)26(29)30/h1-14H/b23-13+,24-14+
Application of LC–MSn in conjunction with mechanism-based stress studies in the elucidation of drug impurity structure: Rapid identification of a process impurity in betamethasone 17-valerate drug substance
Min Li, Mingxiang Lin, Abu Rustum
Journal of Pharmaceutical and Biomedical Analysis 48 (2008) 1451–1456
Development and Validation of Stability-indicating HPLC Method for Betamethoasone Dipropionate and Related Substances in Topical Formulation
A. s. vairale*, p. sivaswaroop1 and s. bandana
Indian Journal of Pharmaceutical Sciences 74(2):107-15