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Irinotecan EP Impurity A

SZ CAT No SZ-I010013
CAS No 103816-16-6
Mol.F. C31H34N4O6
Mol.Wt. 558.6
Inv. Status In Stock
Rel. CAS No 207683-84-9 (HCl salt) ; 883718-83-0 (Sulfate salt)


Chemical Name: (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate (as per EP); (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quin oline-3,14(4H,12H)-dione-9-yl (1,4′-bipiperidine)-1′-carboxylate (as per USP)

Synonym: Irinotecan USP Impurity a

Development and validation of Spectrophotometric method and TLC Densitometric Determination of Irinotecan HCl in pharmaceutical dosage forms
SmitaSharma, Mukesh C.Sharma
Arabian Journal of Chemistry Volume 9, Supplement 2, November 2016, Pages S1368-S1372
 
Development of stability indicating HPLC method for the assay of irinotecan in the presence of degradents
A.K.Srivastava*, K.Pallavi, S.Shamshul, S.C.Khurana
ACAIJ, 10(10) 2011 [665-669]
 
Validated Reverse Phase HPLC Method for the Determination of Irinotecan in Pharmaceutical Dosage Forms
Murali balaram v, venkateswara rao j * ,ramakrishna s # sankar ganesh g # and balamurali krishna t
E-Journal of Chemistry Vol. 4, No.1, pp 128-136