Chemical Name: (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-Hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,5,6,6a,6b,7,8,8a,8b,11a,12,12a,12btetradecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one;
Synonym: Desonide 1,2-Dihydro Analog
Smiles: O=C(CC[C@@]12C)C=C1CC[C@@]([C@]2([H])[C@@H](O)C[C@@]34C)([H])[C@]3([H])C[C@]5([H])[C@@]4(C(CO)=O)OC(C)(C)O5
Inchi: InChI=1S/C24H32O6/c1-4-20-29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,2)21(15)17(27)11-23(16,3)24(19,30-20)18(28)12-25/h7-9,15-17,19-21,25,27H,4-6,10-12H2,1-3H3/t15-,16-,17-,19+,20+,21+,22-,23-,24+/m0/s1
Development of a novel HPLC method for the determination of the impurities in desonide cream and characterization of its impurities by 2D LC-IT-TOF MS
Jian Wanga,b, Shuxian Zhenga, Yu Xua, Haiyan Huc, Minji Shenc, Lan Tang
Journal of Pharmaceutical and Biomedical Analysis 161 (2018) 399–406
Studies on the Stability of Corticosteroids: Degradation of Clobetasol Propionate, Desonide and Hydrocortisone in Topical Formulations by HPLC and UPLC-MS/MS
Kishore Kumar Hotha, Subathra Ramamoorthy1, Hiren Patel
American Journal of Analytical Chemistry, 2020, 11, 147-171