Chemical Name: (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (as per EP & USP)
Synonym: 9-Aminominocycline (EP) ; Tigecycline USP Related Compound B
Smiles: O[C@@](C(O)=C(C1=O)[C@](CC2=C1C(O)=C(N)C=C2N(C)C)([H])C3)(C(C(C(N)=O)=C4O)=O)[C@]3([H])[C@@H]4N(C)C.Cl
Inchi: InChI=1S/C29H37N5O10/c1-29(2,3)31-10-15(35)32-13-9-14(33(4)5)17-18(23(13)38)24(39)16(28(43)44)11(21(17)36)8-12-20(34(6)7)25(40)19(27(30)42)26(41)22(12)37/h9,11,21,31,36H,8,10H2,1-7H3,(H7,30,32,35,37,38,39,40,41,42,43,44)/p+1/t11-,21+/m0/s1
Estimation of related substances in tigecycline by rp-hplc Method
By Mohan, Bavireddi; Sharma, R. S. K.; Rao, S. V. Murali Mohan; Gopal, N. V. S. Venu
From Oriental Journal of Chemistry (2017), 33(5), 2608-2615
Development and validation of an LC-MS/MS method for determination of tigecycline and its epimer in human plasma and its application in a pharmacokinetic study
By Wang, Longyuan; Hu, Xiaoxiao; Zhu, Hong; Zhang, Xiaotian; Wang, Chuan; Han, Zhiwu
From Acta Chromatographica (2016), 28(2), 239-253
Development and validation of a novel HPLC method for quantification of tigecycline in bulk and nanoparticle based suspension
By Geetha, M.; Prakash, Rao B.; Rajendra, C. E.; Chaluvaraju, K. C.; Manjula, B. P.
From Journal of Pharmacy and Chemistry (2015), 9(1), 22-26