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Tacrolimus Impurity VII

SZ目录编号 SZ-T005025
CAS 号 144432-22-4
分子式 C44H69NO12
分子量 804
投资状态 Custom Synthesis


化学名称: (E)-13-Allyl-10, 24-dihydroxy-8-[(E)-2-(4-hydroxy-3-methoxycyclohexy)-1-methylvinyl]-19, 21-dimethoxy-9, 15, 17, 23-tetramethyl-7, 28, 29-trioxa-27-azatetracyclo[23.2.1.120.24.05.27]nonacos-14-ene-6, 12, 26-trione

Solid state compatibility study and characterization of a novel degradation product of tacrolimus in formulation
Tanja Rozman Peterka∗, Rok Grahek, Jure Hren, Andrej Bastarda, Jure Bergles, Urosˇ Urleb
Journal of Pharmaceutical and Biomedical Analysis 110 (2015) 67–75
 
Forced degradation of tacrolimus and the development of a UHPLC method for impurities determination
Tanja Rozman Peterka 1 , Tina Trdan Lušin 1 , Jure Bergles 1 , Zoran Ham 1 , Rok Grahek 1 , and Uroš Urleb 1
Acta Pharm. 69 (2019) 363–380
 
Development and Validation of method for the determination of related substances of Tacrolimus in Tacrolimus Capsules and Degradation Studies
Qingping Shi*1,2, Jianchun Li2 , Feng Ding
International Journal of ChemTech Research Vol.4, No.4, pp 1543-1552,
 
Reutilization of Tacrolimus Extracted from Expired Prograf Capsules: Physical, Chemical, and Pharmacological Assessment
Ziyad Binkhathlan, Mohamed M. Badran, Abdullah Alomrani, Ibrahim A. Aljuffali, Mohammed Alghonaim, Saleh Al-Muhsen, Rabih Halwani & Aws Alshamsan
AAPS PharmSciTech volume 17, pages978–987(2016)