Chemical Name: Propan-2-yl [4-[[2-(methylcarbamoyl)pyridin-4-yl]oxy]phenyl]carbamate (as per EP) Isopropyl (4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate (as per USP)
Synonym: Sorafenib USP Impurity D
Smiles: O=C(NC)C1=NC=CC(OC2=CC=C(NC(OC(C)C)=O)C=C2)=C1
Inchi: InChI=1S/C7H5ClF3N/c8-6-2-1-4(12)3-5(6)7(9,10)11/h1-3H,12H2
Fragmentation pathways and differentiation of positional isomers of sorafenib and structural analogues by ESI-IT-MSn and ESI-Q-TOF-MS/MS coupled with DFT calculations
By Yu, Dandan; Liang, Xianrui
From Journal of Mass Spectrometry (2018), 53(7), 579-589.
Box-Behnken design based statistical modelling for optimization of U PLC-MS/MS method for analysis of sorafenib in bulk and tablets
By Wanii, Tanveer A.; Alanazi, Amer M.; Zargar, Seema; Ahmad, Ajaz; Drawish, Ibrahim A.
From Journal of Computational and Theoretical Nanoscience (2015), 12(10), 3598-3604
Determination of sorafenib in human plasma by HPLC
By Liu, Weifeng; Cao, Pengjian; Zhang, Chunfang; Xia, Dongxia; Che, Shujuan; Lou, Dan; Qiu, Xiangjun
From Zhongguo Xiandai Yingyong Yaoxue (2015), 32(2), 182-185