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Sacubitril Impurity 35

SZ目录编号 SZ-S020043
CAS 号 1810778-75-6
分子式 C20H25NO3
分子量 327.4
投资状态 Custom Synthesis


化学名称: Tert-butyl (S)-(3-([1,1'-biphenyl]-4-yl)-2-hydroxypropyl)carbamate

微笑: O[C@H](CNC(OC(C)(C)C)=O)CC1=CC=C(C2=CC=CC=C2)C=C1

印地语: InChI=1S/C17H19NO2/c1-13(20)18-17(12-19)11-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10,17,19H,11-12H2,1H3,(H,18,20)/t17-/m1/s1

A liquid chromatographic method for separation of sacubitril–valsartan and their stereoisomeric impurities
Lu Zhou,  Liang Zou,  Lili Sun,  Hui Zhang,  Wenkai Hui and  Qiaogen Zou
Anal. Methods, 2018,10, 1046-1053
 
Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS
Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi
Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645
 
Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics
Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud
Chromatographia volume 81, pages139–156(2018)
 
Development and validation of a stability indicating UHPLC method for Sacubitril/Valsartan complex in the presence of impurities and degradation products
Pintu Prajapati, Dhara Bhayani, Priti Mehta.
J App Pharm Sci. 2020; 10(2): 97-107