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Raltegravir EP Impurity A Hydrobromide salt

SZ目录编号 SZ-R009019
CAS 号 1415836-94-0
分子式 C16H19FN4O3 : HBr
分子量 334.4 : 80.9
投资状态 Custom Synthesis
Rel. CAS No 518048-03-8 (free base)


化学名称: 2-(2-aminopropan-2-yl)-N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide Hydrobromide salt (as per EP); 2-(2-Aminopropan-2-yl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide Hydrobromide salt (as per USP)

异名: Raltegravir amine Impurity

微笑: CN1C(C(C)(N)C)=NC(C(NCC2=CC=C(F)C=C2)=O)=C(O)C1=O.Br

Development and validation of stability indicating RP-​HPLC assay method of raltegravir in tablet dosage forms
By Shirisha, V.; Sairaju, B.; Illendula, Santhosh; Dutt, K. Rajeswar
From World Journal of Pharmacy and Pharmaceutical Sciences (2019), 8(10), 668-692
 
Stability indicating reverse-​phase high performance liquid chromatography method for the determination of raltegravir in bulk and pharmaceutical formulation
By Annapurna, Mukthinuthalapati Mathrusri; Teja, Gunnam Ravi; Hemchand, S.; Babu, R. Ravi Chandra
From International Journal of Green Pharmacy (2018), 12(1Suppl.), S177-S180
 
Development and validation of RP-​HPLC method for determination of raltegravir and its impurities in bulk drug and dosage forms
By Balaji, M.; AppaRao, K. M. Ch.; Ramakrishna, K.; Srinivasarao, V.
From Pharma Science Monitor (2014), 5(3Suppl.1), 187-196, 10 pp.