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Posaconazole Impurity 67

SZ目录编号 SZ-P022101
CAS 号 NA
分子式 C44H48F2N8O4
分子量 790.9
投资状态 Custom Synthesis


化学名称: 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3S)-2-(benzyloxy)pentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

微笑: O=C1N([C@@H](CC)[C@H](OCC2=CC=CC=C2)C)N=CN1C3=CC=C(N4CCN(C5=CC=C(OC[C@@H]6CO[C@](C7=CC=C(F)C=C7F)(CN8N=CN=C8)C6)C=C5)CC4)C=C3

印地语: InChI=1S/C15H29O15P/c1-5(13(23)31(24,25)26)27-3-7-9(19)12(22)15(4-17,29-7)30-14-11(21)10(20)8(18)6(2-16)28-14/h5-14,16-23H,2-4H2,1H3,(H2,24,25,26)/t5?,6-,7-,8-,9-,10+,11-,12+,13?,14-,15+/m1/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..