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Posaconazole Impurity 10

SZ目录编号 SZ-P022030
CAS 号 NA
分子式 C37H40F2N8O4 
分子量 698.8
投资状态 Custom Synthesis


化学名称: 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((R)-2-oxopentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one

微笑: O=C(N([C@H](CC)C(C)=O)N=C1)N1C2=CC=C(N3CCN(C4=CC=C(OC[C@@H]5CO[C@@](CN6N=CN=C6)(C7=C(F)C=C(F)C=C7)C5)C=C4)CC3)C=C2

印地语: InChI=1S/C23H23FN6O4S/c1-17-2-5-20(6-3-17)35(31,32)34-11-18-9-23(33-10-18,12-29-15-25-13-27-29)21-7-4-19(8-22(21)24)30-16-26-14-28-30/h2-8,13-16,18H,9-12H2,1H3/t18-,23-/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..