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Posaconazole Enantiomer 2

SZ目录编号 SZ-P022087
CAS 号 NA
分子式 C38H44F2N8O4
分子量 714.8
投资状态 Custom Synthesis


化学名称: 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl) tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2R,3R)-2-hydroxyhexan-3-yl)-2,4-dihydro-3H-1,2,4,-triazol-3-one

微笑: O=C1N([C@H](CCC)[C@H](O)C)N=CN1C2=CC=C(N3CCN(C4=CC=C(OC[C@H]5CO[C@@](C6=CC=C(F)C=C6F)(CN7N=CN=C7)C5)C=C4)CC3)C=C2

印地语: InChI=1S/C38H44F2N8O4/c1-3-4-36(27(2)49)48-37(50)47(26-43-48)32-8-6-30(7-9-32)44-15-17-45(18-16-44)31-10-12-33(13-11-31)51-21-28-20-38(52-22-28,23-46-25-41-24-42-46)34-14-5-29(39)19-35(34)40/h5-14,19,24-28,36,49H,3-4,15-18,20-23H2,1-2H3/t27-,28+,36-,38-/m0/s1

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..