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Posaconazole-D-Glucuronide

SZ目录编号 SZ-P022113
CAS 号 NA
分子式 C43H50F2N8O10
分子量 876.9
投资状态 Custom Synthesis


化学名称: (2S,3S,4S,5R,6R)-6-(1-(((2R,4R)-2-(2,4-difluorophenyl)-4-((4-(4-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazin-1-yl)phenoxy)methyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazol-4-ium-4-yl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate

微笑: O=C1N(C2=CC=C(N3CCN(C4=CC=C(OC[C@H]5C[C@@](C6=C(F)C=C(F)C=C6)(CN7N=C[N+]([C@]8([H])O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]8O)=C7)OC5)C=C4)CC3)C=C2)C=NN1[C@H]([C@@H](O)C)CC

印地语: InChI=1S/2C14H18ClN5O4/c1-8(21)23-5-10(6-24-9(2)22)3-4-20-7-17-13-11(20)12(15)18-14(16)19-13;1-8(21)23-5-10(6-24-9(2)22)3-4-20-7-17-11-12(15)18-14(16)19-13(11)20/h2*7,10H,3-6H2,1-2H3,(H2,16,18,19)

Influence of cyclodextrin on posaconazole stability, release and activity: Improve the utility of the drug
By Santana, Ana Cristina Sousa Gramoza Vilarinho; Nadvorny, Daniela; da Rocha Passos, Taisa Daiany; de La Roca Soares, Monica Felts; Soares-Sobrinho, Jose Lamartine
From Journal of Drug Delivery Science and Technology (2019), 53, 101153
 
Stability-​indicating HPLC method development and structural elucidation of novel degradation products in posaconazole injection by LC-​TOF​/MS, LC-​MS​/MS and NMR
By Yang, Yidi; Zhu, Xi; Zhang, Fei; Li, Wei; Wu, Ying; Ding, Li
From Journal of Pharmaceutical and Biomedical Analysis (2016), 125, 165-177
 
Stability indicating HPLC method for the quantification of posaconazole and its related substances
By Govind, Sampath Kumar Reddy; Nagaraju, Ch. V. S.; Rajan, S. T.; Eshwaraiah, S.; Kishore, M.; Rakesh, M.; Chakravarthy, I. E.
From Pharma Chemica (2014), 6(1), 486-494, 9 pp..