Paroxetine Impurity 8

Paroxetine Impurity 8 is chemically (3S,4S)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-ethoxyphenyl)piperidine hydrochloride. Paroxetine Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Paroxetine Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Paroxetine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Development, validation and transfer into a factory environment of a liquid chromatography tandem mass spectrometry assay for the highly neurotoxic impurity FMTP (4-(4-fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine) in paroxetine active pharmaceutical ingredient (API)
Phil J.Borman, Marion J.Chatfield, Elizabeth L.Crowley, ChristineEckers, David P.Elder, Scott W.Francey, Alice M.-F.Laures, Jean-ClaudeWolff
Journal of Pharmaceutical and Biomedical Analysis Volume 48, Issue 4, 1 December 2008, Pages 1082-1089
 
An Investigation into the Dehydration Behavior of Paroxetine HCl Form I Using a Combination of Thermal and Diffraction Methods: The Identification and Characterization of a New Anhydrous Form
M. Fátima Pina, Min Zhao, João F. Pinto, João J. Sousa, Christopher S. Frampton, Victor Diaz, Osama Suleiman, László Fábián, and Duncan Q. M. Craig
Cryst. Growth Des. 2014, 14, 8, 3774–3782
 
Determination of residual solvents in paroxetine by headspace gas chromatography
abdul rahaman sk, padmavathi sakinala, khaleel n, harekrishna roy
Asian J Pharm Clin Res, Vol 12, Issue 6, 2019, 150-155
 
Spectral Characterization of Degradation Impurities of Paroxetine Hydrochloride Hemihydrate
nirmala munigela, j. moses babu , anjaneyulu yerramilli , naveen kumar kolla , vyas krishnamurthy, vijay vittal mathad
Sci Pharm. 2008; 76; 653–661.

• We need to receive valid purchase order with Bill to & Ship to address.
• The quotation ID needs to be mentioned in the purchase order.
• You will receive order confirmation prior to dispatch which need to be verified for any error in product, pack size, prices.

Delivery time:

• In Stock product will dispatch in 24 h after receipt of purchase order. It usually take 2-3 days to receive products in India and 5-6 working days for export customer depending on destination.
• The custom synthesis products would be dispatched as per quoted timeline.

Shipping:

• There will be 100 USD towards logistic charges per shipment if we used our FedEx. There will not be any charge if we use your FedEx/DHL Account. Depending on part shipment logistic charges will be added.
• For countries dispatch by courier is not allowed where product would be dispatched in cargo mode as per agreed Inco term.

Additional Charges:

• Controlled substance charges need to follow as per quotation. The specific inputs are required for controlled substance because regulatory status will differ based on destination.
• Cold Shipment Charges needs to be considered as per quotation.
• For ice pack there are no additional charges.

Technical Queries:

• All technical queries need to raise within 15 days of product receipt. Thereafter it will be our resolved at our discretion.

Reach to Us:

• All communication will be addressed to standards@synzeal.com
• SynZeal emphasize on formal communication which is required for smooth processing of the purchase order. It helps multiple people to remain informed about all details.
• For specific purpose, there are below e-mail address to be used.
  • For New products # standards@synzeal.com
  • Order confirmation # order@synzeal.com
  • Open Order Status # projects@synzeal.com
  • Data related Query # support@synzeal.com
  • Invoice Related Query # sales@synzeal.com
  • Logistic Documents # exports@synzeal.com (For export customer only)
• It is recommended to include standards@synzeal.com always in CC while communicating to other e-mail address.
• SynZeal is committed for promptly responding all communication however if sometime urgent comes us you can use our WhatsApp customer care channel (+91 70690 37751) to reach to customer support team. You can also request call back on WhatsApp and our customer support team will reach to you in defined timeframe.