化学名称: (4-(Methyl(nitroso)amino)benzoyl)-L-glutamic acid
微笑: O=C(N[C@H](C(O)=O)CCC(O)=O)C1=CC=C(N(C)N=O)C=C1
印地语: InChI=1S/C19H19N9O6/c20-15-14-16(26-19(21)25-15)22-7-10(23-14)8-28(27-34)11-3-1-9(2-4-11)17(31)24-12(18(32)33)5-6-13(29)30/h1-4,7,12H,5-6,8H2,(H,24,31)(H,29,30)(H,32,33)(H4,20,21,22,25,26)/t12-/m0/s1
Identification and Quantitation of Impurities in Methotrexate
dulal c. chatterji, altice g. frazier, and joseph f. gallell
Journal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624
determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection
mark c. roach, philippe gozel and richard n. zare
Journal of Chromatography, 426 (1988) 129-140
Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples
Forough Karami , Sara Ranjbar , Younes Ghasemi , Manica Negahdaripour
Journal of Pharmaceutical Analysis 9 (2019) 373-391
Perspectives of Methotrexate-Based Radioagents for Application in Nuclear Medicine
Paweł Krzysztof Halik,* Przemysław Kozmin ́ ski, and Ewa Gniazdowska
Mol. Pharmaceutics 2021, 18, 1, 33–43