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Enzalutamide D3

SZ目录编号 SZ-E015D04
CAS 号 1443331-82-5
分子式 C21H13D3F4N4O2S
分子量 467.5
投资状态 Custom Synthesis


化学名称: 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N-(methyl-d3)benzamide

Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method
Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai Ouyang
Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
 
Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification
Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari
Cryst. Growth Des. 2018, 18, 7, 3774–3780
 
Quantitative Study of Impurities in Enzalutamide and Identification, Isolation, Characterization of Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and NMR Analyses
Ainan Zhou1,2 · Lejun Ruan1  · Gengli Duan2  · Jianqi Li
Chromatographia volume 81, pages1519–1531(2018)
 
Validation of a method for quantifying enzalutamide and its major metabolites in human plasma by LC–MS/MS
Daniel Bennett, Jacqueline A Gibbons, Roelof Mol, Yoshiaki Ohtsu & Clark Williard
Bioanalysis (2014) 6(6), 737–744