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Cefuroxime Axetil

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SZ目录编号 SZ-C086011
CAS 号 64544-07-6
分子式 C20H22N4O10S
分子量 510.5
投资状态 In Stock
Rel. CAS No 102672-56-0 (HCl salt)


Disclaimer

SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

化学名称: (1RS)-1-(Acetyloxy)ethyl (6R,7R)-3-[(carbamoyloxy)methyl]-7-[[(Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]-oct-2-ene-2-carboxylate (as per EP); (5‐Thia‐1‐azabicyclo[4.2.0]oct‐2‐ene‐2‐carboxylic acid, 3‐[[(aminocarbonyl)oxy]methyl]‐ 7‐[[2‐furanyl(methoxyimino)acetyl]amino]‐8‐oxo‐, 1‐(acetyloxy)ethyl ester, [6R‐[6a,7b(Z)]]‐) (as per USP)

异名: Cefuroxime 1-Acetoxyethyl Ester

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

微笑: O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@H](NC(/C(C3=CC=CO3)=N\OC)=O)C1=O)OC(OC(C)=O)C

Cefuroxime Axetil is chemically (1RS)-1-(Acetyloxy)ethyl (6R,7R)-3-[(carbamoyloxy)methyl]-7-[[(Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]-oct-2-ene-2-carboxylate (as per EP); (5‐Thia‐1‐azabicyclo[4.2.0]oct‐2‐ene‐2‐carboxylic acid, 3‐[[(aminocarbonyl)oxy]methyl]‐ 7‐[[2‐furanyl(methoxyimino)acetyl]amino]‐8‐oxo‐, 1‐(acetyloxy)ethyl ester, [6R‐[6a,7b(Z)]]‐) (as per USP). It is also known as Cefuroxime 1-Acetoxyethyl Ester. Cefuroxime Axetil is supplied with detailed characterization data compliant with regulatory guideline. Cefuroxime Axetil can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cefuroxime.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Liquid chromatography-​tandem mass spectrometry method for the determination of cefuroxime axetil diastereoisomers: application to stability-​indicating method
By Sharaf El-Din, Mohie M. K.; Nassar, Mohamed W. I.; Attia, Khalid A. M.; El Demellawy, Maha A.; Kaddah, Mohamed M. Y.
From Journal of the Iranian Chemical Society (2021), 18(9), 2505-2515
 
Content determination of cefuroxime in peritoneal dialysis solution by HPLC and compatible stability of the mixture
By Li, Cheng; Wu, Xiao-juan; Feng, Lian-jie; Mai, Jia-hui; Zhang, Kai-li
From Zhongguo Yaofang (2012), 23(25), 2378-2379

Specific stability indicating assay method for the determination of cefuroxime sodium in pharmaceutical formulation by UV-​Vis Spectrophotometer
By Devkhile, A. B.; Shaikh, K. A.
From International Journal of Pharmacy and Technology (2011), 3(1), 1609-1622

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