Nome Químico: (Z)-2-cyano-3-hydroxy-N-(3-(trifluoromethyl)phenyl)but-2-enamide
Sorrisos: O=C(/C(C#N)=C(O)/C)NC1=CC(C(F)(F)F)=CC=C1
Inchi: InChI=1S/C82H90Cl2N10O23/c1-37(2)13-10-8-6-7-9-11-14-59(100)88-68-70(102)71(103)73(81(111)112)117-82(68)116-72-57-31-42-32-58(72)115-55-24-19-41(29-49(55)83)69(101)67-80(110)92-65(75(105)86-25-12-26-94(4)5)47-33-43(95)34-53(98)60(47)46-28-39(17-22-51(46)96)63(77(107)93-67)89-78(108)64(42)90-79(109)66-48-35-45(36-54(99)61(48)84)114-56-30-40(18-23-52(56)97)62(85-3)76(106)87-50(74(104)91-66)27-38-15-20-44(113-57)21-16-38/h15-24,28-37,50,62-71,73,82,85,95-99,101-103H,6-14,25-27H2,1-5H3,(H,86,105)(H,87,106)(H,88,100)(H,89,108)(H,90,109)(H,91,104)(H,92,110)(H,93,107)(H,111,112)/t50-,62-,63-,64-,65+,66+,67+,68-,69-,70-,71+,73+,82-/m1/s1
Quality-by-design-based development and validation of a stability-indicating UPLC method for quantification of teriflunomide in the presence of degradation products and its application to in-vitro dissolution
Nukendra Prasad Nadella,Venkata Nadh Ratnakaram & N. Srinivasu
Journal of Liquid Chromatography & Related Technologies Volume 40, 2017 - Issue 10 Pages 517-527
Development of Validated Stability Indicating HPTLC Method for the Estimation of Teriflunomide in Bulk and Tablet Dosage Form
Karmankar, Snehal; Tajne, M.
Current Pharmaceutical Analysis, Volume 16, Number 7, 2020, pp. 814-822(9)