Chemical Name: (1RS)-2-[(1,1-Dimethylethyl)amino]-1-[4-hydroxy-3-(methoxymethyl)phenyl]ethanol (as per EP)
Synonym: Salbutamol BP Impurity M
Smiles: COCC1=CC(C(O)CNC(C)(C)C)=CC=C1O
Inchi: InChI=1/C13H20ClNO3.ClH/c1-13(2,3)15-6-11(17)8-4-9(7-16)12(18)10(14)5-8;/h4-5,11,15-18H,6-7H2,1-3H3;1H
Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography
AmandineDispasaVincentDesfontainebBertylAndriaPierreLebrunacDorinaKotonidAdrianClarkedDavyGuillarmebPhilippeHuberta
Journal of Pharmaceutical and Biomedical Analysis
Volume 134, 5 February 2017, Pages 170-180
Evolved gas analysis during thermal degradation of salbutamol sulphate
Fabio Sonvico, Victoria Coleman, Daniela Traini & Paul M. Young
Journal of Thermal Analysis and Calorimetry volume 120, pages789–794 (2015)
A chromatography-free synthesis of racemic salbutamol hemisulfate
AgatheVanoostLaurentPetit
Tetrahedron Letters
Volume 61, Issue 28, 9 July 2020, 152126