Chemical Name: 1,1′-[Oxybis[methylene(4-hydroxy-1,3-phenylene)]]bis[2-[(1,1-dimethylethyl)amino]ethanol] (as per EP)
Synonym: Salbutamol BP Impurity F ; Salbutamol Dimer Ether ; Albuterol USP Related Compound E
Smiles: CC(NCC(C1=CC(COCC2=C(O)C=CC(C(O)CNC(C)(C)C)=C2)=C(O)C=C1)O)(C)C
Inchi: InChI=1/C20H27NO3/c1-20(2,3)21(12-15-7-5-4-6-8-15)13-19(24)16-9-10-18(23)17(11-16)14-22/h4-11,19,22-24H,12-14H2,1-3H3
Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography
AmandineDispasaVincentDesfontainebBertylAndriaPierreLebrunacDorinaKotonidAdrianClarkedDavyGuillarmebPhilippeHuberta
Journal of Pharmaceutical and Biomedical Analysis
Volume 134, 5 February 2017, Pages 170-180
Evolved gas analysis during thermal degradation of salbutamol sulphate
Fabio Sonvico, Victoria Coleman, Daniela Traini & Paul M. Young
Journal of Thermal Analysis and Calorimetry volume 120, pages789–794 (2015)
A chromatography-free synthesis of racemic salbutamol hemisulfate
AgatheVanoostLaurentPetit
Tetrahedron Letters
Volume 61, Issue 28, 9 July 2020, 152126