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  • Osimertinib

Osimertinib Related Products

SynZeal is a leading innovator in pharmaceutical reference standards. We supply high-quality Reference Standards of Osimertinib, pharmacopeial and non-pharmacopeial Osimertinib impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Osimertinib impurities reference standards are useful in pharmaceutical research. They are useful in product development, ANDA and DMF filing, quality control (QC), method validation, and stability studies. It is also useful in the identification of unknown impurities and the assessment of genotoxic potential.

Osimertinib-related products are thoroughly characterized. Osimertinib products are supplied with detailed COA & analytical data meeting regulatory compliance. We can also provide EP/USP traceable standards based on your requirements. The supplied products are re-tested at regular intervals.

Pharmaceutical Reference Standards

Osimertinib

Picture of Osimertinib
CAT No: SZ-O014001
CAS No: 1421373-65-0
Mol.F. : C28H33N7O2
Mol.Wt. : 499.6
Inv. Status: Custom Synthesis
Rel. CAS No : 2088858-63-1 (HCl salt) ; 2185782-00-5 (HBr salt) ; 1421373-66-1 (mesylate salt)
SZ-O014001
CAS No:1421373-65-0
Mol.F.: C28H33N7O2
Mol.Wt.: 499.6
Inv. Status: Custom Synthesis
Rel. CAS No : 2088858-63-1 (HCl salt) ; 2185782-00-5 (HBr salt) ; 1421373-66-1 (mesylate salt)

Osimertinib Impurity A

Picture of Osimertinib Impurity A
CAT No: SZ-O014002
CAS No: 1421373-98-9
Mol.F. : C27H31N7O2
Mol.Wt. : 485.6
Inv. Status: In Stock
Rel. CAS No : 2469006-57-1 (HCl Salt)
SZ-O014002
CAS No:1421373-98-9
Mol.F.: C27H31N7O2
Mol.Wt.: 485.6
Inv. Status: In Stock
Rel. CAS No : 2469006-57-1 (HCl Salt)

Osimertinib Impurity G

Picture of Osimertinib Impurity G
CAT No: SZ-O014003
CAS No: 2044702-39-6
Mol.F. : C25H26N6O2
Mol.Wt. : 442.5
Inv. Status: In Stock
SZ-O014003
CAS No:2044702-39-6
Mol.F.: C25H26N6O2
Mol.Wt.: 442.5
Inv. Status: In Stock

Osimertinib Impurity I

Picture of Osimertinib Impurity I
CAT No: SZ-O014004
CAS No: 2044702-55-6
Mol.F. : C22H24N6O : HCl
Mol.Wt. : 388.5 : 36.5
Inv. Status: In Stock
Rel. CAS No : 1801616-92-1 (free base)
SZ-O014004
CAS No:2044702-55-6
Mol.F.: C22H24N6O : HCl
Mol.Wt.: 388.5 : 36.5
Inv. Status: In Stock
Rel. CAS No : 1801616-92-1 (free base)

Osimertinib Impurity J

Picture of Osimertinib Impurity J
CAT No: SZ-O014005
CAS No: 1820891-36-8
Mol.F. : C22H22N6O3
Mol.Wt. : 418.5
Inv. Status: In Stock
SZ-O014005
CAS No:1820891-36-8
Mol.F.: C22H22N6O3
Mol.Wt.: 418.5
Inv. Status: In Stock

Osimertinib N-Oxide Impurity 1

Picture of Osimertinib N-Oxide Impurity 1
CAT No: SZ-O014006
CAS No: 2411395-22-5
Mol.F. : C28H33N7O3
Mol.Wt. : 515.6
Inv. Status: Custom Synthesis
SZ-O014006
CAS No:2411395-22-5
Mol.F.: C28H33N7O3 
Mol.Wt.: 515.6
Inv. Status: Custom Synthesis

Osimertinib N-Oxide Impurity 2

Picture of Osimertinib N-Oxide Impurity 2
CAT No: SZ-O014007
CAS No: 1975982-94-5
Mol.F. : C28H33N7O3
Mol.Wt. : 515.6
Inv. Status: In Stock
SZ-O014007
CAS No:1975982-94-5
Mol.F.: C28H33N7O3
Mol.Wt.: 515.6
Inv. Status: In Stock

N-Acryloyl Osimertinib

Picture of N-Acryloyl Osimertinib
CAT No: SZ-O014008
CAS No: 1932710-29-6
Mol.F. : C31H35N7O3
Mol.Wt. : 553.7
Inv. Status: Custom Synthesis
SZ-O014008
CAS No:1932710-29-6
Mol.F.: C31H35N7O3
Mol.Wt.: 553.7
Inv. Status: Custom Synthesis

Osimertinib N,N'-Dioxide

Picture of Osimertinib N,N'-Dioxide
CAT No: SZ-O014009
CAS No: 2411395-23-6
Mol.F. : C28H33N7O4
Mol.Wt. : 531.6
Inv. Status: Custom Synthesis
SZ-O014009
CAS No:2411395-23-6
Mol.F.: C28H33N7O4
Mol.Wt.: 531.6
Inv. Status: Custom Synthesis

Osimertinib Impurity 1

Picture of Osimertinib Impurity 1
CAT No: SZ-O014010
CAS No: 1009298-59-2
Mol.F. : C25H30N6O3
Mol.Wt. : 462.6
Inv. Status: Custom Synthesis
SZ-O014010
CAS No:1009298-59-2
Mol.F.: C25H30N6O3
Mol.Wt.: 462.6
Inv. Status: Custom Synthesis

Osimertinib Impurity 2

Picture of Osimertinib Impurity 2
CAT No: SZ-O014011
CAS No: NA
Mol.F. : C20H19N5O2
Mol.Wt. : 361.4
Inv. Status: Custom Synthesis
SZ-O014011
CAS No:NA
Mol.F.: C20H19N5O2
Mol.Wt.: 361.4
Inv. Status: Custom Synthesis

Osimertinib Dimer Impurity 1

Picture of Osimertinib Dimer Impurity 1
CAT No: SZ-O014012
CAS No: NA
Mol.F. : C53H64N14O3
Mol.Wt. : 945.2
Inv. Status: Under Synthesis
SZ-O014012
CAS No:NA
Mol.F.: C53H64N14O3
Mol.Wt.: 945.2
Inv. Status: Under Synthesis

Osimertinib Dimer Impurity 2

Picture of Osimertinib Dimer Impurity 2
CAT No: SZ-O014013
CAS No: NA
Mol.F. : C57H68N14O4
Mol.Wt. : 1013.3
Inv. Status: Custom Synthesis
SZ-O014013
CAS No:NA
Mol.F.: C57H68N14O4
Mol.Wt.: 1013.3
Inv. Status: Custom Synthesis

Osimertinib Dimer Impurity 3

Picture of Osimertinib Dimer Impurity 3
CAT No: SZ-O014014
CAS No: NA
Mol.F. : C56H66N14O4
Mol.Wt. : 999.2
Inv. Status: Custom Synthesis
SZ-O014014
CAS No:NA
Mol.F.: C56H66N14O4
Mol.Wt.: 999.2
Inv. Status: Custom Synthesis

Osimertinib N Desmethyl Impurity

Picture of Osimertinib N Desmethyl Impurity
CAT No: SZ-O014015
CAS No: 1421373-99-0
Mol.F. : C27H31N7O2
Mol.Wt. : 485.6
Inv. Status: In Stock
Rel. CAS No : 2309762-40-9 (HCl salt)
SZ-O014015
CAS No:1421373-99-0
Mol.F.: C27H31N7O2
Mol.Wt.: 485.6
Inv. Status: In Stock
Rel. CAS No : 2309762-40-9 (HCl salt)

Osimertinib Impurity 5

Picture of Osimertinib Impurity 5
CAT No: SZ-O014017
CAS No: NA
Mol.F. : C34H43N8O2
Mol.Wt. : 595.8
Inv. Status: Custom Synthesis
SZ-O014017
CAS No:NA
Mol.F.: C34H43N8O2
Mol.Wt.: 595.8
Inv. Status: Custom Synthesis

Osimertinib Dimer Impurity 4

Picture of Osimertinib Dimer Impurity 4
CAT No: SZ-O014018
CAS No: NA
Mol.F. : C56H67N14O4
Mol.Wt. : 1000.3
Inv. Status: Custom Synthesis
SZ-O014018
CAS No:NA
Mol.F.: C56H67N14O4
Mol.Wt.: 1000.3
Inv. Status: Custom Synthesis

Osimertinib Amine Impurity

Picture of Osimertinib Amine Impurity
CAT No: SZ-O014019
CAS No: 1421372-66-8
Mol.F. : C25H31N7O
Mol.Wt. : 445.6
Inv. Status: In Stock
Rel. CAS No : 2786805-72-7 (mesylate salt) ; 2699784-52-4 (HCl salt)
SZ-O014019
CAS No:1421372-66-8
Mol.F.: C25H31N7O
Mol.Wt.: 445.6
Inv. Status: In Stock
Rel. CAS No : 2786805-72-7 (mesylate salt) ; 2699784-52-4 (HCl salt)

Osimertinib N-Methylacrylamide Impurity

Picture of Osimertinib N-Methylacrylamide Impurity
CAT No: SZ-O014020
CAS No: 2850389-35-2
Mol.F. : C30H33N7O3
Mol.Wt. : 539.6
Inv. Status: Custom Synthesis
SZ-O014020
CAS No:2850389-35-2
Mol.F.: C30H33N7O3
Mol.Wt.: 539.6
Inv. Status: Custom Synthesis

Osimertinib Methoxy Impurity

Picture of Osimertinib Methoxy Impurity
CAT No: SZ-O014021
CAS No: NA
Mol.F. : C29H37N7O3
Mol.Wt. : 531.7
Inv. Status: Custom Synthesis
SZ-O014021
CAS No:NA
Mol.F.: C29H37N7O3
Mol.Wt.: 531.7
Inv. Status: Custom Synthesis

Osimertinib Mesylate

Picture of Osimertinib Mesylate
CAT No: SZ-O014022
CAS No: 1421373-66-1
Mol.F. : C28H33N7O2 : CH4O3S
Mol.Wt. : 499.6 : 96.1
Inv. Status: In Stock
Rel. CAS No : 1421373-65-0 (free base) ; 2088858-63-1 (HCl salt) ; 2185782-00-5 (HBr salt)
SZ-O014022
CAS No:1421373-66-1
Mol.F.: C28H33N7O2 : CH4O3S
Mol.Wt.: 499.6 : 96.1
Inv. Status: In Stock
Rel. CAS No : 1421373-65-0 (free base) ; 2088858-63-1 (HCl salt) ; 2185782-00-5 (HBr salt)

Osimertinib 2-Amide Impurity

Picture of Osimertinib 2-Amide Impurity
CAT No: SZ-O014023
CAS No: 2213409-62-0
Mol.F. : C23H20FN5O2
Mol.Wt. : 417.4
Inv. Status: Custom Synthesis
SZ-O014023
CAS No:2213409-62-0
Mol.F.: C23H20FN5O2
Mol.Wt.: 417.4
Inv. Status: Custom Synthesis

Osimertinib Acetyl Impurity

Picture of Osimertinib Acetyl Impurity
CAT No: SZ-O014024
CAS No: 2227103-37-7
Mol.F. : C27H33N7O2
Mol.Wt. : 487.6
Inv. Status: In Stock
SZ-O014024
CAS No:2227103-37-7
Mol.F.: C27H33N7O2
Mol.Wt.: 487.6
Inv. Status: In Stock

Osimertinib Impurity 7

Picture of Osimertinib Impurity 7
CAT No: SZ-O014026
CAS No: 1075705-01-9
Mol.F. : C7H7FN2O3
Mol.Wt. : 186.1
Inv. Status: Custom Synthesis
Rel. CAS No : 2995393-72-9 (mesylate salt)
SZ-O014026
CAS No:1075705-01-9
Mol.F.: C7H7FN2O3
Mol.Wt.: 186.1
Inv. Status: Custom Synthesis
Rel. CAS No : 2995393-72-9 (mesylate salt)

Osimertinib Impurity 8

Picture of Osimertinib Impurity 8
CAT No: SZ-O014027
CAS No: 1032452-86-0
Mol.F. : C13H10ClN3
Mol.Wt. : 243.7
Inv. Status: Custom Synthesis
SZ-O014027
CAS No:1032452-86-0
Mol.F.: C13H10ClN3
Mol.Wt.: 243.7
Inv. Status: Custom Synthesis

Osimertinib Impurity 9

Picture of Osimertinib Impurity 9
CAT No: SZ-O014028
CAS No: 1421373-36-5
Mol.F. : C28H34ClN7O2
Mol.Wt. : 536.1
Inv. Status: In Stock
SZ-O014028
CAS No:1421373-36-5
Mol.F.: C28H34ClN7O2
Mol.Wt.: 536.1
Inv. Status: In Stock

Osimertinib Impurity 10

Picture of Osimertinib Impurity 10
CAT No: SZ-O014029
CAS No: NA
Mol.F. : C29H34N6O3
Mol.Wt. : 514.6
Inv. Status: Custom Synthesis
SZ-O014029
CAS No:NA
Mol.F.: C29H34N6O3
Mol.Wt.: 514.6
Inv. Status: Custom Synthesis

Osimertinib Impurity 11

Picture of Osimertinib Impurity 11
CAT No: SZ-O014030
CAS No: NA
Mol.F. : C23H21N5O3
Mol.Wt. : 415.5
Inv. Status: Under Synthesis
SZ-O014030
CAS No:NA
Mol.F.: C23H21N5O3
Mol.Wt.: 415.5
Inv. Status: Under Synthesis

Osimertinib β-lactam Impurity

Picture of Osimertinib β-lactam Impurity
CAT No: SZ-O014034
CAS No: NA
Mol.F. : C28H33N7O2
Mol.Wt. : 499.6
Inv. Status: Custom Synthesis
SZ-O014034
CAS No:NA
Mol.F.: C28H33N7O2
Mol.Wt.: 499.6
Inv. Status: Custom Synthesis

Osimertinib Impurity 12

Picture of Osimertinib Impurity 12
CAT No: SZ-O014035
CAS No: 2364486-24-6
Mol.F. : C22H18N4
Mol.Wt. : 338.4
Inv. Status: Custom Synthesis
SZ-O014035
CAS No:2364486-24-6
Mol.F.: C22H18N4
Mol.Wt.: 338.4
Inv. Status: Custom Synthesis

Osimertinib Impurity 13

Picture of Osimertinib Impurity 13
CAT No: SZ-O014036
CAS No: 2364486-23-5
Mol.F. : C13H10ClN3
Mol.Wt. : 243.7
Inv. Status: Custom Synthesis
SZ-O014036
CAS No:2364486-23-5
Mol.F.: C13H10ClN3
Mol.Wt.: 243.7
Inv. Status: Custom Synthesis

Osimertinib Impurity 14

Picture of Osimertinib Impurity 14
CAT No: SZ-O014037
CAS No: 1569986-91-9
Mol.F. : C7H7FN2O3
Mol.Wt. : 186.1
Inv. Status: Custom Synthesis
SZ-O014037
CAS No:1569986-91-9
Mol.F.: C7H7FN2O3
Mol.Wt.: 186.1
Inv. Status: Custom Synthesis

Osimertinib Impurity 15

Picture of Osimertinib Impurity 15
CAT No: SZ-O014038
CAS No: 2092773-15-2
Mol.F. : C7H7FN2O3
Mol.Wt. : 186.1
Inv. Status: Custom Synthesis
SZ-O014038
CAS No:2092773-15-2
Mol.F.: C7H7FN2O3
Mol.Wt.: 186.1
Inv. Status: Custom Synthesis

Osimertinib Impurity 16

Picture of Osimertinib Impurity 16
CAT No: SZ-O014039
CAS No: 1421372-67-9
Mol.F. : C25H29N7O3
Mol.Wt. : 475.6
Inv. Status: Custom Synthesis
SZ-O014039
CAS No:1421372-67-9
Mol.F.: C25H29N7O3
Mol.Wt.: 475.6
Inv. Status: Custom Synthesis

Osimertinib Impurity 17

Picture of Osimertinib Impurity 17
CAT No: SZ-O014040
CAS No: 2772439-88-8
Mol.F. : C28H33N7O2
Mol.Wt. : 499.6
Inv. Status: Custom Synthesis
SZ-O014040
CAS No:2772439-88-8
Mol.F.: C28H33N7O2
Mol.Wt.: 499.6
Inv. Status: Custom Synthesis

Stable Isotopes And Metabolites

Osimertinib D6

Picture of Osimertinib D6
CAT No: SZ-O014D01
CAS No: 1638281-44-3
Mol.F. : C28H27D6N7O2
Mol.Wt. : 505.7
Inv. Status: Custom Synthesis
SZ-O014D01
CAS No:1638281-44-3
Mol.F.: C28H27D6N7O2
Mol.Wt.: 505.7
Inv. Status: Custom Synthesis

Possible Nitroso Standards

N-Nitroso Osimertinib

Picture of N-Nitroso Osimertinib
CAT No: SZ-O014025
CAS No: NA
Mol.F. : C28H32N8O3
Mol.Wt. : 528.6
Inv. Status: Inquire
SZ-O014025
CAS No:NA
Mol.F.: C28H32N8O3
Mol.Wt.: 528.6
Inv. Status: Inquire

N-Nitroso Osimertinib Impurity A

Picture of N-Nitroso Osimertinib Impurity A
CAT No: SZ-O014031
CAS No: NA
Mol.F. : C27H30N8O3
Mol.Wt. : 514.6
Inv. Status: Inquire
SZ-O014031
CAS No:NA
Mol.F.: C27H30N8O3
Mol.Wt.: 514.6
Inv. Status: Inquire

Osimertinib Nitroso Impurity 3

Picture of Osimertinib Nitroso Impurity 3
CAT No: SZ-O014032
CAS No: NA
Mol.F. : C27H30N8O3
Mol.Wt. : 514.6
Inv. Status: Custom Synthesis
SZ-O014032
CAS No:NA
Mol.F.: C27H30N8O3
Mol.Wt.: 514.6
Inv. Status: Custom Synthesis

Osimertinib N-Nitroso N Desmethyl Impurity

Picture of Osimertinib N-Nitroso N Desmethyl Impurity
CAT No: SZ-O014033
CAS No: NA
Mol.F. : C27H30N8O3
Mol.Wt. : 514.6
Inv. Status: Custom Synthesis
SZ-O014033
CAS No:NA
Mol.F.: C27H30N8O3
Mol.Wt.: 514.6
Inv. Status: Custom Synthesis