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Atenolol Amine Impurity

SZ目录编号 SZ-A035016
CAS 号 1042779-86-1
分子式 C10H14N2O3
分子量 210.2
投资状态 Custom Synthesis


化学名称: 4-(3-Amino-2-hydroxypropoxy)benzamide

微笑: O=C(N)C1=CC=C(OCC(O)CN)C=C1

印地语: InChI=1S/C67H77Cl2N9O24/c1-24(2)13-36(78(5)6)60(90)76-50-52(84)27-8-11-39(33(68)15-27)98-41-17-29-18-42(56(41)102-66-57(55(87)54(86)43(23-79)100-66)101-45-22-67(4,71)58(88)25(3)97-45)99-40-12-9-28(16-34(40)69)53(85)51-64(94)75-49(65(95)96)32-19-30(80)20-38(82)46(32)31-14-26(7-10-37(31)81)47(61(91)77-51)74-62(92)48(29)73-59(89)35(21-44(70)83)72-63(50)93/h7-12,14-20,24-25,35-36,43,45,47-55,57-58,66,79-82,84-88H,13,21-23,71H2,1-6H3,(H2,70,83)(H,72,93)(H,73,89)(H,74,92)(H,75,94)(H,76,90)(H,77,91)(H,95,96)/t25-,35-,36+,43+,45-,47+,48+,49?,50+,51-,52+,53+,54+,55-,57+,58+,66-,67-/m0/s1

The assay and resolution of the beta-blocker atenolol from its related impurities in a tablet pharmaceutical dosage form
Zen pawlak* and Brian j. clark
Journal of Pharmaceutical & Biomedical Analysis Vol. 10, No. 5, pp. 329-334,1992
 
Removal of Atenolol and Isoproturon in Aqueous Solutions by Adsorption in a Fixed-Bed Column
JoséLuis Sotelo, Gabriel Ovejero, Araceli Rodríguez, Silvia Á lvarez, and Juan García
Ind. Eng. Chem. Res. 2012, 51, 5045−5055
 
A simple, selective, and sensitive gas chromatography-mass spectrometry method for the analysis of five process-related impurities in atenolol bulk drug and capsule formulations
Ambavaram Vijaya Bhaskar Reddy  Zulkifli Yusop  Jafariah Jaafar  Azmi Bin Aris  Zaiton Abdul Majid
JSS Volume 40, Issue 15 Pages: 3016-3182 August 2017
 
A Sensitive and Selective GC–MS Method for Analysis of Process-Related Genotoxic Impurities in Atenolol
Yogeshwar Reddy Mamilla1,3,&, Kista Reddy Chetyala3 , Ramesh Venna2 , Raju Gajjela2 , Kishore Katragadda1 , Saravanan Govindasamy1 , Suryanarayana Mulukutla1 , Debashish Datta
Chromatographia 2010, 71, 733–736
 
Development and validation of liquid chromatographic method for atenolol and its related substance
Nandini R. Pai* and Swapnali Suhas Patil
Der Pharmacia Sinica, 2013, 4(2):76-84