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Abacavir EP Impurity A

SZ目录编号 SZ-A049002
CAS 号 136470-79-6
分子式 C14H18N6O
分子量 286.3
投资状态 Custom Synthesis
Rel. CAS No 935777-88-1 (Sulfate salt)


化学名称: [(1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl]methanol (as per EP)

异名: (1R,4S)-Abacavir ; Ent-Abacavir

微笑: [H][C@]1(C=C[C@]([H])(CO)C1)N2C3=NC(N)=NC(NC4CC4)=C3N=C2

印地语: InChI=1S/C31H26FN3O7/c1-31(32)25(42-28(38)22-15-9-4-10-16-22)23(19-40-27(37)21-13-7-3-8-14-21)41-29(31)35-18-17-24(34-30(35)39)33-26(36)20-11-5-2-6-12-20/h2-18,23,25,29H,19H2,1H3,(H,33,34,36,39)/t23-,25+,29+,31+/m1/s1

Stability indicating RP-​HPLC method development and validation for determination of abacavir sulphate in tablet dosage form
By Ithape, Aniket B.; Deshpande, Padmanabh B.; Shelke, Priyanka
From International Journal of Pharmacy and Pharmaceutical Research (2020), 17(4), 670-680
 
A new stability indicating method was developed and validated for the simultaneous estimation of Lamivudine and Abacavir in tablet dosage form by RP-​HPLC
By Rajamahanti, Santoshi G.; Annapurna, N.; Santosh, T.; Durga, B.; Raziya, S. K.
From Research Journal of Pharmaceutical, Biological and Chemical Sciences (2017), 8(3), 407-421
 
A validated stability-​indicating RP-​HPLC method for abacavir sulfate in the presence of degradation products, its process-​related impurities and identification of oxidative degradant by LC-​MS​/MS
By Ragham, Pramod Kumar; Chandrasekhar, Kothapalli B.; Reddy, J. Rudraprasad; Kasturi, Krishna Mohan
From Indo American Journal of Pharmaceutical Research (2015), 5(1), 463-473