Chemical Name: 5-Amino-1H-imidazole-4-carboxamide hydrochloride
Synonym: Dacarbazine USP Related Compound A ; Temozolomide Aminoimidazole Impurity
Smiles: O=C(N)C1=C(N)NC=N1.Cl
Inchi: InChI=1S/C6H5N5O3/c1-10-6(14)11-2-7-3(5(12)13)4(11)8-9-10/h2H,1H3,(H,12,13)
Design of experiment based validated stability indicating RP-HPLC method of temozolomide in bulk and pharmaceutical dosage forms
Anam Khan, Syed Sarim Imam, Mohd Aqil, Yasmin Sultana, Asgar Ali, Khalid Khan
Beni-Suef University Journal of Basic and Applied Sciences Volume 5, Issue 4, December 2016, Pages 402-408
Identification and Physicochemical Characteristics of Temozolomide Process-Related Impurities
Marta Łaszcz, Marek Kubiszewski, Łukasz Jedynak, Monika Kaczmarska, Łukasz Kaczmarek, Wojciech Łuniewski, Krzysztof Gabarski, Anna Witkowska, Krzysztof Kuziak and Maura Malińska
Molecules 2013, 18, 15344-15356
Development and Validation of Simultaneous Detrmination of Anastrozole and Temozolomide in Pharmaceutical Dosage Forms
V.N. Daphal*, G. Holkar, R. Yadav & M. Rokade
International Journal of Theoretical & Applied Sciences, 4(2): 48-55(2012)
A Stability Indicating UPLC Method for Determination of Temozolomide and its Related Substances in Bulk and Finished Dosage Forms
ramu ivaturi, t. manikya sastry and s. satyaveni
Asian Journal of Chemistry; Vol. 30, No. 9 (2018), 1971-1977