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Sitagliptin Phosphate Monohydrate

N° de SZ CAT SZ-S009020
Número CAS 654671-77-9
Mol.F. C16H15F6N5O : H3O4P : H2O
Peso Molecular 407.3 : 98.0 :18.0
Status de Fatura In Stock
Rel. CAS No 486460-32-6 (free base) ; 654671-78-0 (Phosphate salt)


Nome Químico: (R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate

Sorrisos: FC1=CC(C[C@](N)([H])CC(N2CCN3C(C2)=NN=C3C(F)(F)F)=O)=C(F)C=C1F.O=[P](O)(O)O.O

Inchi: InChI=1S/C23H23F6N5O9/c24-10-6-12(26)11(25)4-8(10)3-9(30-22(41)43-20-17(38)15(36)16(37)18(42-20)19(39)40)5-14(35)33-1-2-34-13(7-33)31-32-21(34)23(27,28)29/h4,6,9,15-18,20,36-38H,1-3,5,7H2,(H,30,41)(H,39,40)/t9-,15?,16?,17?,18?,20?/m1/s1

Determination of chemical stability of sitagliptin by LC-UV, LC-MS and FT-IR methods
Anna Gumieniczek, Anna Berecka, Tomasz Mroczek, Krzysztof Wojtanowski, Kinga Dąbrowska, Katarzyna Stępień
Journal of Pharmaceutical and Biomedical Analysis Volume 164, 5 February 2019, Pages 789-807
 
Development and validation of stability indicating assay method by HPLC for the analysis of sitagliptin phospahte in bulk drug substances
Meher Vijay Dalawai , Paul Douglas Sanasi and Hemant Kumar Sharma
Journal of Chemical and Pharmaceutical Research, 2015, 7(10):781-787
 
Enantiometric separation of sitagliptin in a fixed dose combination formula of sitagliptin and metformin by a chiral liquid chromatographic method
nagadeep jaishetty*, kamaraj palanisamy, arthanareeswari maruthapillai
Int J Pharm Pharm Sci, Vol 11, Issue 6, 66-71