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Sitagliptin N-Phoshate Impurity

N° de SZ CAT SZ-S009030
Número CAS NA
Mol.F. C16H16F6N5O4P 
Peso Molecular 487.3
Status de Fatura Custom Synthesis


Nome Químico: (R)-(4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)phosphoramidic acid

Sorrisos: FC1=C(C[C@@H](NP(O)(O)=O)CC(N2CC3=NN=C(C(F)(F)F)N3CC2)=O)C=C(F)C(F)=C1

Inchi: InChI=1S/C11H12F3NO2.ClH/c1-17-11(16)4-7(15)2-6-3-9(13)10(14)5-8(6)12;/h3,5,7H,2,4,15H2,1H3;1H/t7-;/m1./s1

Determination of chemical stability of sitagliptin by LC-UV, LC-MS and FT-IR methods
Anna Gumieniczek, Anna Berecka, Tomasz Mroczek, Krzysztof Wojtanowski, Kinga Dąbrowska, Katarzyna Stępień
Journal of Pharmaceutical and Biomedical Analysis Volume 164, 5 February 2019, Pages 789-807
 
Development and validation of stability indicating assay method by HPLC for the analysis of sitagliptin phospahte in bulk drug substances
Meher Vijay Dalawai , Paul Douglas Sanasi and Hemant Kumar Sharma
Journal of Chemical and Pharmaceutical Research, 2015, 7(10):781-787
 
Enantiometric separation of sitagliptin in a fixed dose combination formula of sitagliptin and metformin by a chiral liquid chromatographic method
nagadeep jaishetty*, kamaraj palanisamy, arthanareeswari maruthapillai
Int J Pharm Pharm Sci, Vol 11, Issue 6, 66-71