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Sitagliptin Enamine Amide Impurity

N° de SZ CAT SZ-S009040
Número CAS NA
Mol.F. C18H15F6N5O2 
Peso Molecular 447.3
Status de Fatura Custom Synthesis


Nome Químico: (Z)-N-(4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)but-2-en-2-yl)acetamide

Sorrisos: FC1=CC(F)=C(C/C(NC(C)=O)=C/C(N2CCN3C(C2)=NN=C3C(F)(F)F)=O)C=C1F

Inchi: InChI=1S/C20H19F6N5O3/c1-10(32)31(11(2)33)13(5-12-6-15(22)16(23)8-14(12)21)7-18(34)29-3-4-30-17(9-29)27-28-19(30)20(24,25)26/h6,8,13H,3-5,7,9H2,1-2H3/t13-/m0/s1

Determination of chemical stability of sitagliptin by LC-UV, LC-MS and FT-IR methods
Anna Gumieniczek, Anna Berecka, Tomasz Mroczek, Krzysztof Wojtanowski, Kinga Dąbrowska, Katarzyna Stępień
Journal of Pharmaceutical and Biomedical Analysis Volume 164, 5 February 2019, Pages 789-807
 
Development and validation of stability indicating assay method by HPLC for the analysis of sitagliptin phospahte in bulk drug substances
Meher Vijay Dalawai , Paul Douglas Sanasi and Hemant Kumar Sharma
Journal of Chemical and Pharmaceutical Research, 2015, 7(10):781-787
 
Enantiometric separation of sitagliptin in a fixed dose combination formula of sitagliptin and metformin by a chiral liquid chromatographic method
nagadeep jaishetty*, kamaraj palanisamy, arthanareeswari maruthapillai
Int J Pharm Pharm Sci, Vol 11, Issue 6, 66-71