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Sacubitril Impurity 21

N° de SZ CAT SZ-S020024
Número CAS 1817838-91-7
Mol.F. C25H31NO4
Peso Molecular 409.5
Status de Fatura In Stock


Nome Químico: Ethyl (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate

Sorrisos: CCOC(/C(C)=C/[C@H](NC(OC(C)(C)C)=O)CC(C=C1)=CC=C1C2=CC=CC=C2)=O

A liquid chromatographic method for separation of sacubitril–valsartan and their stereoisomeric impurities
Lu Zhou,  Liang Zou,  Lili Sun,  Hui Zhang,  Wenkai Hui and  Qiaogen Zou
Anal. Methods, 2018,10, 1046-1053
 
Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS
Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi
Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645
 
Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics
Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud
Chromatographia volume 81, pages139–156(2018)
 
Development and validation of a stability indicating UHPLC method for Sacubitril/Valsartan complex in the presence of impurities and degradation products
Pintu Prajapati, Dhara Bhayani, Priti Mehta.
J App Pharm Sci. 2020; 10(2): 97-107